FJVIS 35. Sexual Dysfunction After Aortoiliac Surgery: Does Endovascular Repair Preserve Erectile Function?

Male sexual dysfunction after aortoiliac surgery is a distressing complication. Erectile dysfunction and ejaculatory function postoperatively are mainly related to the methods of exposure and dissection of the aorta and iliac arteries because it is the preferred passage area of the upper hypogastric plexus, the main crossroads of the pathways of sympathetic nerves with pelvic intent. The purpose was to determine the incidence of erectile dysfunction in patients with aortoiliac occlusive disease and to compare the change in erectile function after open surgery and endovascular repair.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research

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Publication date: Available online 24 May 2020Source: EXPLOREAuthor(s): HongJuan Li, Haoming Huang, Wenjie Long, Junling Zuo, Hongqiang Huang
Source: EXPLORE: The Journal of Science and Healing - Category: Complementary Medicine Source Type: research
HDAC1 is involved in a form of DNA repair, but levels decline with age, as well as in Alzheimer's disease. This leads to a greater accumulation of unrepaired oxidative DNA damage in neurons. Researchers here note that increased activation of HDAC1 appears to improve cognitive function via a reduction in this oxidative DNA damage. An HDAC1 activator drug has been tested as a treatment for dementia, but caused serious side-effects. Better compounds or other approaches may be able to obtain similar benefits without the harms. There are several members of the HDAC family of enzymes, and their primary function is to m...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Conditions:   Erectile Dysfunction;   Penile Diseases Intervention:   Diagnostic Test: shear Wave Elastosonography Sponsor:   University Of Perugia Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Mitral Regurgitation Functional Intervention:   Device: MitraClip implantation Sponsor:   IRCCS San Raffaele Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Contributors : Nada Zaidan ; Evangelia Diamanti ; Katrin OttersbachSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe aim of this study was to examine the whole transcriptome of pools of 20 cells of Gata3-expressing AGM subpopulations (haematopoietic [HC], mesenchymal [MC], sympathetic nervous system [SNS], and endothelial [EC]) and compare them to their non-Gata3 expressing counterparts
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
CONCLUSIONS: Trials of antidepressants may be driven mainly by commercial interests, focusing on prevalent diseases and everyday problems. No one can live a full life without experiencing several of the problems for which these drugs were tested. Antidepressants, sometimes called happy pills, could be seen as the modern version of Aldous Huxley's soma pill intended to keep everyone happy in the "Brave New World". PMID: 32444565 [PubMed - as supplied by publisher]
Source: International Journal of Risk and Safety in Medicine - Category: Drugs & Pharmacology Tags: Int J Risk Saf Med Source Type: research
In this study, the resistant bacterial flora was screened from activated sludge and immobilized by sodium alginate (SAB). Nano-Fe3O4 was coated on biochar (BC@Fe3O4) to prevent agglomerating in soil. X-ray diffraction (XRD) and scanning electron microscope (SEM) were utilized to characterize BC@Fe3O4. Results demonstrated that the treatment of biochemical system (SAB + BC@Fe3O4 + PS) presented the maximum degradation rate about 92.56% within 24 days of incubation and improved soil microecology. The 16S rDNA sequences analysis of soil microorganisms showed a significantly different abundance and a simila...
Source: Environmental Pollution - Category: Environmental Health Authors: Tags: Environ Pollut Source Type: research
Conclusions Dysautonomic symptoms frequently occuring in α-synucleinopathies comprise cardiovascular, gastrointestinal, urogenital and thermoregulatory disturbances. These symptoms reduce quality of life and worsen prognosis. The understanding of their pathophysiology, as well as the detection of α-synuclein deposition and autonomic dysfunction in the premotor stages of α-synucleinopathies may be key for identifying novel treatment targets and improving clinical outcomes. While causative treatment is not yet available, improvement of quality of life can be achieved by personalized symptomatic treatment r...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusions Aging leads to a progressive decrease in androgen production that, in turn, leads to the development of LOH, defined by significant low T serum levels (in the lowest quartile) in the presence of signs and symptoms of hypogonadism (51). LOH could be due to both testicular and hypothalamic-pituitary dysfunction (32), and ED is one of its main symptoms. ED in LOH is linked to increased oxidative stress, subclinical inflammation, and subsequent endothelial dysfunction (101). In elderly men, it has been shown that LOH is also linked to lower cAMP pool and to an alteration of the cGMP signaling pathway. PDE5 gene l...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusion: The occurence of erectile dysfunction is significantly more prevalent among neurologically disabled men, particularly those with lesions below S2–S4, than among men without neurologic disability. Considering the prevalence of erectile dysfunction among neurologically disabled men, sexual functioning should be regularly evaluated during acute and long-term rehabilitation, and any existing sexual dysfunction should be addressed in the treatment plan. Introduction Penile erection is a neurovascular event characterized by the dilation of arteries that cause the corpora cavernosa and corpora spongiosum of the ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Medical Issues Neurologic Systems and Symptoms Neurology Neuromuscular Disease Original Research Neurogenic SD; Erectile Dysfunction; sexual health; Quality of life Source Type: research
More News: Endovascular Repair (EVAR) | Erectile Dysfunction | Gastroschisis Repair | Reflex Sympathetic Dystrophy | Sexual Dysfunction | Surgery