OCS-01 in Treating Inflammation and Pain in Post-cataract Patients

Conditions:   Inflammation Corneal;   Pain, Postoperative Intervention:   Drug: OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL Sponsor:   Oculis Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Drs. Agrawal and Khurana raise valid points. We would like to clarify that the patients were masked to which group they were assigned and were  not aware of whether they were receiving a ketorolac-soaked bandage contact lens or a plain lens. This is important because, as Drs. Agrawal and Khurana rightly point out, the placebo effect could play an important role in pain management.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Letter Source Type: research
Shetty et  al.1 evaluated the effect of a bandage contact lens soaked in ketorolac ophthalmic 0.45% solution on pain modulation in patients having transepithelial photorefractive keratectomy (PRK). The authors did not mention whether the patients in the treatment group and no treatment group were masked. It is known that when patients are aware of the allocation to an experimental intervention or to a comparator including a placebo, they experience, report, or record greater benefits than when they are unaware of the assignment.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Letter Source Type: research
AbstractPurposeTo compare the perceived pain and estimated operative duration among patients undergoing bilateral cataract surgery and to demonstrate correlations with the surgical interval and the demographic and medical characteristics of the patients.MethodsA total of 466 patients with cataract who underwent ocular surgery were included. The patients estimated the perceived operative duration and pain they felt during the operation at two times, immediately after surgery and on the first postoperative day; pain was scored using a visual analog scale ranging from 0 (no pain) to 10 (unbearable pain). Patients undergoing b...
Source: International Ophthalmology - Category: Opthalmology Source Type: research
A 45-year-old South Asian woman presented with a 2-month history of acute onset of unilateral dry-eye symptoms with significant irritation and blurry vision in the left eye. She reported increasing difficulty using the computer, itching, and eye pain after work in both eyes but significantly more pronounced in the left eye. Artificial tears provided no relief of symptoms in the left eye. Initially, an optometric physician, who diagnosed her with acute corneal abrasion in the left eye, treated her with lubricating drops and ointments.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Consultation section: Cataract Source Type: research
Conclusion: Stenotrophomonas maltophilia is a rare infectious agent associated with intravitreal injection and may present 1 month after treatment.
Source: Retinal Cases and Brief Reports - Category: Opthalmology Tags: Case Report Source Type: research
Condition:   Ocular Inflammation and Pain Interventions:   Drug: APP13007, 0.05%;   Drug: APP13007, 0.1%;   Drug: APP13007 Placebo, 0.05%;   Drug: APP13007 Placebo, 0.1% Sponsor:   Formosa Pharmaceuticals, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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