Adjunctive memantine for opioid use disorder treatment: A systematic review

The objective of this systematic review is to assess the evidence available to determine the safety and efficacy of memantine as treatment for OUD. Pubmed (1946-August 2019) and Embase (1947-August 2019) were queried using the following search terms: opioid-related disorders, opioids, substance withdrawal syndrome, withdrawal syndrome, opiate addiction, opiate, opiate dependence, opiate substitution treatment, managed opioid withdrawal, or drug withdrawal and memantine.
Source: Journal of Substance Abuse Treatment - Category: Addiction Authors: Source Type: research

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Pain, memory problems and nicotine addiction are formidable problems that have quite different consequences. But in terms of what’s happening in the brain that causes people to suffer from each, they share a close connection. And now scientists say one drug might be able to help people with all three of these problems. Estimates suggest 2 million people in the U.S. suffered from an opioid abuse disorder in 2015 (the most recent year with data available), about 5 million Americans are currently living with Alzheimer’s disease and more than 36 million Americans are currently cigarette smokers (more than half of w...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
— Hundreds of companies around the globe, now including Elon Musk’s Neuralink and even Facebook,  are researching and developing new ways to help brain owners be smarter, sharper, and healthier. What explains this flurry of activity? Where may it be headed? To help you understand what’s going on, let me highlight five key facts that emerged from the recent SharpBrains Virtual Summit, where 200+ participants in 16 countries shared and discussed the latest about neurotech­nolo­gy, brain health and digital health.   Fact 1. There are 7.5 billion human brains out there, a...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology Akili Baycrest Brain-health BrainHQ Claritas Mindsciences Click Therapeutics cogmed Cogniciti cognifit digital health Educational Testing Service Elon Musk Facebook Headsp Source Type: blogs
When President Obama signed the 21st Century Cures Act on December 13th, he signed into law one of the most sweeping efforts to provide additional programs and funding for health conditions and innovation in America, including cancer, Alzheimer’s disease, opioid addiction, medical devices, access to new drugs, and mental health. The Cures Act includes the major provisions of the Senate mental health compromise bill, Mental Health Reform Act of 2016, as well as a few additional provisions from the House’s over-reaching Helping Families in Mental Health Crisis Act of 2016 bill. While the bill goes a long way in h...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness Policy and Advocacy 21st century cures Helping Families in Crisis mental health reform act Mental Illness Source Type: blogs
This article was originally published on Mindful. Read the original article. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
LITTLE ROCK - Arkansas Gov. Asa Hutchinson, the former head of the federal Drug Enforcement Administration, accused medical marijuana supporters on Monday of misleading voters about the drug's benefits as they promote two new ballot measures that would legalize pot for some patients. Joined by some of the state's top doctors, the Republican governor said the measures "do not lead to good medicine" and said they would circumvent the federal process for studying, approving and regulating new drugs. Arkansas voters narrowly rejected legalizing medical marijuana four years ago. "We don't vote on cancer...
Source: Arkansas Business - Health Care - Category: American Health Source Type: news
Conclusion: Despite the significant burden mental disorders impose on society, investment and pharmaceutical innovation in this disease area remains comparatively low. Policymakers should consider new strategies to stimulate public and private investment in the research and development of novel and effective therapies to treat schizophrenia and other mental disorders. Introduction Over the last two decades, there have been remarkable breakthroughs in healthcare. These breakthroughs include the development of novel pharmaceutical treatments that have significantly improved outcomes for patients suffering from various medica...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Bipolar Disorder Current Issue Drug Development Mental Disorders Mood Disorders Original Research Psychiatry Psychopharmacology disease burden expenditures major depressive disorder pharmaceutical innovation research and developmen Source Type: research
This article was originally published on Recovery Brands' Pro Talk/Pro Corner http://www.rehabs.com/pro-talk-articles/yes-benzos-are-bad-for-you/ Allen Frances is a professor emeritus at Duke University and was the chairman of the DSM-IV task force. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Science - The Huffington Post - Category: Science Source Type: news
Last night at a Town Hall in South Carolina, Republican presidential candidate Jeb Bush answered a question about drug use and abuse with a broader appeal. "We ought to have a focus on the brain," he said. "You think about the challenges that play out in our society, all of these things relate to the brain." Gov. Bush mentioned addiction, and Alzheimer's. I'd like to add mental health and learning disorders to that list. Just this past week the Duchess of Cambridge guest edited the Huffington Post UK with a focus on children's mental health, and First Lady Michelle Obama wrote that we must "change ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
As the New Horizons spacecraft made its historic flight to Pluto and some scientists explored the far reaches of our solar system, others were making some incredible advances in their exploration of the inner workings of the mind.  Studies published this year shed light on the mysteries of the brain and human behavior, and began paving the way for new treatments to mental and neurological health problems, ranging from addiction to autism to Alzheimer's disease.  Here are eight fascinating things we learned about the human mind in 2015.  1. Smartphones are wildly distracting.  Americans are spending more...
Source: Science - The Huffington Post - Category: Science Source Type: news
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