Potential causes of cognitive alterations in temporal lobe epilepsy.

Potential causes of cognitive alterations in temporal lobe epilepsy. Behav Brain Res. 2019 Oct 16;:112310 Authors: Laetitia C Abstract Spatial and non-spatial memories are key processes whereby we process our environment on a daily basis, coding space, time and items to form unique memories. Both types of memory involve distributed and complex temporal lobe (TL) networks. In this review, we will discuss potential causes of spatial and non-spatial memory deficits, taking the example of temporal lobe epilepsy (TLE), a widespread neurological disorder characterized by cognitive comorbidities, in both animal models and TLE patients. We will start by briefly introducing TLE, then highlight by which underlying mechanisms TLE impairs TL-dependent cognitive functions. PMID: 31629002 [PubMed - as supplied by publisher]
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research