Hyperactivity and Reduced Activation of Anterior Hippocampus in Early Psychosis.

CONCLUSIONS: Anterior hippocampal hyperactivity in early-psychosis patients appears to limit effective recruitment of this region during task performance. These findings provide novel support for the anterior hippocampus as a therapeutic target in the treatment of cognitive deficits in psychosis.
PMID: 31623459 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - October 17, 2019 Category: Psychiatry Authors: McHugo M, Talati P, Armstrong K, Vandekar SN, Blackford JU, Woodward ND, Heckers S Tags: Am J Psychiatry Source Type: research