Nutraceutical potential of tree flowers: a comprehensive review on biochemical profile, health benefits, and utilization

Publication date: Available online 9 October 2019Source: Food Research InternationalAuthor(s): Dave Jaydeep Pinakin, Vikas Kumar, Sheenam Suri, Rakesh Sharma, Manisha KaushalAbstractA numerous types of tree flowers are present in nature and few of them such as Rhdodendron, Bauhinia, Mahua, Gulmohar, Palash, Sesbania, Woodfordia, Simbal, etc. are being utilized traditionally as food and medicine by the localities of India. These flowers are rich in phytochemical (flavonoids, anthocyanins, phenolic acids, carotenoids, tannins, saponins) and possessing numerous health benefits (antioxidant activity, anti-inflammation, anti-cancer activity, anti-diabetic activity, hepatoprotective activity). However, because of the low availability (i.e. short blooming period and at limited places) and poor post-harvest life, these flowers are commonly utilized by the local people as food and medicines during their respective flowering times only. A few attempts have been made toward the utilization of some tree flowers (Mahduca longifolia, Rhododendron arboretum), but others are still unexplored and need to be exploited to achieve food and nutritional security as well increase the opportunity of employment and improvement in the socio-economic status of the local tribes. Therefore, to achieve this, the present review was aimed to review and document the status of common edible tree flowers, their phytochemicals potential and, health benefits as well as their utilization as food and medicines.Gra...
Source: Food Research International - Category: Food Science Source Type: research

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ConclusionThis is the first report on the synthesis of two novel ginsenosides, namely glucosyl-ginsenoside Rh2 and diglucosyl-ginsenoside Rh2 from Rh2 by utilizing recombinant glycosyltransferase isolated from L. rhamnosus. Moreover, diglucosyl-ginsenoside Rh2 might be a new candidate for treatment of inflammation, obesity and skin whiting, and especially for anticancer.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Authors: Lega IC, Lipscombe LL Abstract Obesity and diabetes have both been associated with an increased risk of cancer. In the face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer rates. Factors such as hyperinsulinemia, chronic inflammation, anti-hyperglycemic medications and shared risk factors have all been identified as potential mechanisms underlying the relationship. The most common obesity- and diabetes-related cancers are endometrial, colorectal and post menopausal breast cancers. In this review, we summarize the existing evidence that describes the complex relations...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
Fewer biopsies among men receiving antidiabetic medications may explain the lower prostate cancer risk in men with diabetes.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
ConclusionsBy this study, we found that studies on sarcopenia, the gaps of sarcopenia research in Iran, and highlighted the research priorities for future works. The outcome of the present research is to ultimately improve the health, quality of life and well-being of sarcopenic people.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
Publication date: Available online 13 November 2019Source: Clinica Chimica ActaAuthor(s): Xiao Yang, Weinan Pan, Gaosheng Xu, Linxi ChenAbstractMitophagy is an autophagic process through which damaged or dysfunctional mitochondria are specifically degraded to maintain cellular homeostasis. It is highly regulated by various signaling pathways such as the PTEN-induced putative kinase 1 (PINK1)/Parkin and NIP3-like protein X (NIX)/BNIP3 pathways. Additionally, it plays a crucial role in inducing some pathological processes. Notably, some evidence suggesting the association of mitophagy with the occurrence of chronic diseases ...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
We present a narrative review of HCC in Africa, discussing present and future trends. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Liver Disease - Category: Gastroenterology Authors: Tags: Review Article Source Type: research
Background: Insulin resistance, the primary mechanism of metabolic syndrome, promotes gastric carcinogenesis. Metabolic syndrome is associated with sarcopenia. We aimed to investigate the association between sarcopenia and gastric carcinogenesis, including precancerous conditions such as atrophic gastritis (AG), intestinal metaplasia (IM), and dysplasia.Methods: The study included adult patients who underwent gastroduodenoscopy at a checkup center. AG and IM were evaluated using endoscopy. Based on muscle mass, sarcopenia was defined as a skeletal muscle index
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Authors: Ohara N, Kobayashi M, Ikeda Y, Hoshi T, Morita S, Kanefuji T, Yagi K, Suda T, Takada T, Hasegawa G, Sato Y, Hirano K, Kosugi SI Abstract A 70-year-old man with insulinoma-associated antigen-2 autoantibodies developed diabetes mellitus (DM) without ketoacidosis after starting nivolumab to treat advanced gastric cancer. He subsequently exhibited preserved insulin-secretion capacity for over one year. Immune-checkpoint inhibitors (ICIs) infrequently cause type 1 DM associated with the rapid loss of insulin secretion and ketoacidosis as an immune-related adverse event. ICIs may also cause non-insulin-dependent...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
This article presents the original descriptions of some recent physics mechanisms (based on the thermodynamic, kinetic, and quantum tunnel effects) providing stable 2H/1H isotope fractionation, leading to the accumulation of particular isotopic forms in intra- or intercellular space, including the molecular effects of deuterium interaction with 18O/17O/16O, 15N/14N, 13C/12C, and other stable biogenic isotopes. These effects were observed mainly at the organelle (mitochondria) and cell levels. A new hypothesis for heavy nonradioactive isotope fractionation in living systems via neutron effect realization is discussed. The c...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
AbstractBackground and AimsThe features of non-viral, nonalcohol hepatocellular carcinoma (NBNC-HCC) remain elusive. The aim of this study was to investigate this clinical characteristics and overall survival of NBNC-HCC compared to hepatitis B- (HBV-HCC) and hepatitis C-related (HCV-HCC) HCC.MethodsWe analyzed the etiologies, fibrosis stages, clinical data, and outcomes of newly diagnosed patients with HCC.ResultsA total of 1777 HCC patients were recruited, including 332 patients with NBNC-HCC, 682 patients with HBV-HCC, 680 patients with HCV-HCC, and 83 patients with HBV/HCV HCC. Patients with NBNC-HCC were older (69.9 &...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
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