Lichen Planus Pemphigoides Mimicking Toxic Epidermal Necrolysis

This report describes a 70-year-old woman with LPP who presented with extensive erosions mimicking TEN. This case also highlights the need to consider important etiologies such as drug-induced and paraneoplastic LPP.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Extraordinary Case Report Source Type: research

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Stiff-person syndrome (SPS) is a rare progressive autoimmune disorder with marked neuromuscular involvement. Until the present, three main sub-types of SPS are known, namely the classic SPS, SPS variants which include focal, segmental and Jerky SPS and the paraneoplastic SPS [1] which all have diverse clinical presentations but the commonest symptoms include pain, disabling muscle stiffness, periodic muscular cramps and gait problems [2]. We are grateful to El-Abassi et [3] for their recently published article in September 2019 in The Journal of Neurological Sciences on stiff person syndrome.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Tags: Letter to the Editor Source Type: research
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
ConclusionsNeurological cancer increased the risk for subsequent BP by 2.4-fold, with a relatively short gap of 4.5  years.
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Conclusions The clinical trials discussed here, which include several trials investigating novel therapeutic targets, demonstrate that translational research in pemphigus and pemphigoid is a fast-growing field. We thus expect that several novel treatments will be shortly available for the treatment of pemphigus and pemphigoid patients. Given the high, and thus far unmet, medical need in this field (110), this is highly encouraging and will hopefully improve the quality of life of the affected patients. In addition to the compounds and targets described here, several new targets have been recently identified in preclinical...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: December 2017 Source:Actas Dermo-Sifiliográficas (English Edition), Volume 108, Issue 10 Author(s): A. Tirado-Sánchez, A. Bonifaz Paraneoplastic pemphigus (PNP), a subset of pemphigus, is a unique autoimmune blistering condition that can affect multiple organs other than the skin. It is a life-threatening disease associated with an underlying malignancy, most commonly of lymphoproliferative origin. The clinical picture may resemble pemphigus, pemphigoid, erythema multiforme, graft-versus-host disease, or lichen planus. The earliest and most consistent finding is a painful, severe, chronic a...
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
faz A Abstract Paraneoplastic pemphigus (PNP), a subset of pemphigus, is a unique autoimmune blistering condition that can affect multiple organs other than the skin. It is a life-threatening disease associated with an underlying malignancy, most commonly of lymphoproliferative origin. The clinical picture may resemble pemphigus, pemphigoid, erythema multiforme, graft-versus-host disease, or lichen planus. The earliest and most consistent finding is a painful, severe, chronic and often recalcitrant stomatitis. Treatment of PNP is difficult. Immunosuppressive agents are required to decrease blistering, and treating...
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Authors: Tags: Actas Dermosifiliogr Source Type: research
This article is protected by copyright. All rights reserved. PMID: 28213962 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Research Letter Source Type: research
This article is protected by copyright. All rights reserved. PMID: 27436786 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
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