New analysis shows that patients with Type 2 diabetes and mild renal impairment had similar improvement in blood sugar control and experienced less hypoglycemia with JANUVIA (sitagliptin) compared to sulfonylurea

(GCI Health NY) Merck, known as MSD outside the United States and Canada, today announced results from a post-hoc pooled analysis showing patients with Type 2 diabetes and mild renal impairment treated with JANUVIA (sitagliptin) 100 mg once-daily achieved similar blood sugar reductions as those treated with the sulfonylureas glipizide or glimepiride, with significantly fewer events of hypoglycemia, and with weight loss instead of weight gain. Results were presented at the American Diabetes Association 73rd Scientific Sessions.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

Related Links:

CONCLUSION: Roux-en-Y gastric bypass successfully reduced weight, BMI, and comorbidities and medication use and cost at 24 months in Brazilian patients treated in the public Unified Health System.
Source: Clinics - Category: General Medicine Source Type: research
Conclusions: Prediagnosis use of metformin dose ≤1500 mg/d is associated with longer overall survival of elderly diabetic HCC patients.
Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research
Abstract: Gingivitis and periodontitis are associated with a negative impact on Oral Health Related Quality of Life (OHRQoL), exerting a significant influence on aspects related to the patients' function and esthetics. Periodontitis has been associated with several systemic conditions, including adverse pregnancy outcomes, cardiovascular diseases, type 2 diabetes mellitus (DM), respiratory disorders, fatal pneumonia in hemodialysis patients, chronic renal disease and metabolic syndrome. The aim of this paper was to review the results of different periodontal treatments and their impacts on patients' OHRQoL and systemic hea...
Source: Brazilian Oral Research - Category: Dentistry Source Type: research
Publication date: Available online 8 April 2020Source: Meta GeneAuthor(s): Muhammad Tarek Abdel Ghafar, Khaled Hamed Shalaby, Hanaa Ibrahim Okda, Fatma H. Rizk
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
ConclusionsThe presence of FA among T2DM patients implied a worse glycaemic control. Microvascular complications and depressive symptoms were higher among these patients.
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
AbstractIntroductionTo evaluate the efficacy and safety of dulaglutide 0.75 and 1.5  mg in patients with type 2 diabetes mellitus (T2DM) by baseline glycated hemoglobin (HbA1c) 
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
Publication date: Available online 8 April 2020Source: Journal of Taibah University Medical SciencesAuthor(s): Amira Nasser AlJaber, Ibrahim Sales, Turky H. Almigbal, Syed Wajid, Mohammed Ali Batais
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
Publication date: Available online 8 April 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Lulu Zhang, Lei Bao, Yuqian Li, Chongjian Wang, Xiaokang Dong, Tanko Abdulai, Xiu Yang, Mengying Fan, Songyang Cui, Wen Zhou, Zhenxing Mao, Wenqian Huo, Dandan Wei, Linlin Li
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
CONCLUSIONS: A significant positive correlation exists between HDI and obesity. As policy-makers attempt to improve the general welfare of the people, they should be aware of potential unwanted effects of development on the risk of obesity and overweight among the population. PMID: 32268464 [PubMed - as supplied by publisher]
Source: Journal of Preventive Medicine and Public Health - Category: International Medicine & Public Health Tags: J Prev Med Public Health Source Type: research
Authors: Maranta F, Cianfanelli L, Cianflone D Abstract Diabetes mellitus is constantly increasing worldwide. Vascular complications are the most common in the setting of long-standing disease, claiming the greatest burden in terms of morbidity and mortality. Glucotoxicity is involved in vascular damage through different metabolic pathways, such as production of advanced glycation end-products, activation of protein kinase C, polyol pathway activation and production of reactive oxygen species. Vascular complications can be classified according to the calibre of the vessels involved as microvascular (such as diabeti...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
More News: Diabetes | Diabetes Type 2 | Endocrinology | Glimepiride | Glipizide | Health | International Medicine & Public Health | Januvia | Merck | Weight Loss