Possibility of minimizing gluten intolerance by co-consumption of some fruits – a case for positive food synergy?

Publication date: Available online 17 October 2019Source: Trends in Food Science & TechnologyAuthor(s): Isuri A. Jayawardana, Carlos A. Montoya, Warren C. McNabb, Mike J. BolandBackgroundStaple cereals and their products are important foods. Many cereals contain an important protein group, gluten, which provides structure to bakery products and pasta. Gluten proteins have an unusual amino acid composition, containing high proline and glutamine contents. These amino acids confer resistance to proteolysis by gastrointestinal tract enzymes, producing indigestible proline- and glutamine-rich peptides that can trigger immunogenic reactions responsible for gluten-related health disorders. These disorders represent a serious public health issue, affecting approximately 5% of the global population. The prescription of a gluten-free diet (GFD) is the only accepted therapy for gluten-related health disorders.Scope and approachAdherence to a GFD remains a difficult goal for many reasons. Alternative approaches have been proposed to supplement or substitute a GFD. Among them, the use of gluten-specific enzymes to degrade immunogenic peptides has shown promising results. Most of the enzymes used in this approach are of microbial origin. Identification of natural alternatives is a timely requirement.Key findingsSeveral enzymes of microbial origin have been identified that are claimed to digest gluten in the human gastrointestinal tract. However, only a few claim to be able to digest immuno...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research