Meta-analysis of the effect of CYP2B6, CYP2A6, UGT2B7 and CAR polymorphisms on efavirenz plasma concentrations

ConclusionsThis meta-analysis provides the overall effect size for the impact ofCYP2B6 rs3745274 andNR1I3 rs2307424 on efavirenz pharmacokinetics. The analysis also indicates that some previous associations were not significant when interrogated across studies.
Source: Journal of Antimicrobial Chemotherapy - Category: Microbiology Source Type: research