Two new glycoalkaloids from Stephania succifera

Publication date: December 2019Source: Phytochemistry Letters, Volume 34Author(s): Shi-Ting Wang, Wen-Qi Qian, Peng He, Mei-Qing Feng, Yun Kang, Ya-Qin Wang, Jian-Ming HuangAbstractTwo new glycoalkaloids, manshurienine C (1) and 8-oxotetrahy-corydalmine-1-O-β-D-glucopyranoside (2), along with eleven known alkaloids (3–13), were isolated from the tubers of Stephania succifera. Their structures were elucidated by spectroscopic methods, including NMR and MS spectra. Compounds 5, 6, 8, and 10 showed in vitro antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research