Molecular pathway analysis associates alterations in obesity related genes and antipsychotic-induced weight gain.

CONCLUSIONS: The molecular pathway composed from high-risk obesity genes, was shown to overlap with genetics of patients who gained > 7% weight gain during the CATIE trial. This suggests that genes related to obesity, composes a pathway of increased risk of excessive antipsychotic-induced weight gain. Further independent analyses are warranted that may confirm or clarify the possible reasoning behind. PMID: 31619305 [PubMed - as supplied by publisher]
Source: Acta Neuropsychiatrica - Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research