What my surgical menopause can teach pharmacists about HRT

Substance misuse pharmacist Lucy Skea had a surgical menopause at 39 years old; here ’s what she thinks pharmacists should know to support patients considering hormone replacement therapy (HRT).
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research

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aro M Abstract AIM: While the short-term effects of hormonal events on gingival inflammation have been well described, long-term effects on the periodontium have received less attention. The aim of this cross-sectional population-based study was to evaluate the association between hormone-related events and periodontitis in a representative sample of the post-menopausal women of South Korea. MATERIALS AND METHODS: A total of 10,273 postmenopausal women representative of 6.1 million of Koreans were examined. Periodontitis and severe periodontitis were defined according to the Community Periodontal Index (CPI‚Č...
Source: Journal of Clinical Periodontology - Category: Dentistry Authors: Tags: J Clin Periodontol Source Type: research
In the middle of the night, I wake up feeling warm. I open the window and pull my hair back into a ponytail and drink some water. Then I glance at my phone, delete a few things, and see some spam. I hit unsubscribe and go back to bed. Then I lie there thinking, What if by opening that spam email I got myself hacked? What if I just sent everyone in my contact list a Burger King ad at two in the morning? Now wide awake, I move on to other concerns: my parents’ health, my stepson’s college tuition, pending deadlines. Hours roll by. I tackle real-life math problems: how many weeks I have before getting my next free...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Gen X healthy sleep insomnia Source Type: news
Did you ever wonder why medical research seems to flip-flop so often? Eggs used to be terrible for your health; now they’re not so bad. Stomach ulcers were thought to be due to stress and a “type A personality” but that’s been disproven. I was taught that every postmenopausal woman should take hormone replacement therapy to prevent heart disease and bone loss; now it’s considered way too risky. It can make you question every bit of medical news you hear. But maybe that’s not such a bad thing. Questioning what you read or hear is reasonable. And maybe medical reversals — when new re...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Medical Research Prevention Tests and procedures Source Type: blogs
CONCLUSION: Obesity was not found to correlate strongly with the progression or remission of CIN. Obese postmenopausal women may still be affected by a persistence of the disease. Continuing cervical cytology monitoring should be recommended for such patients. Silent high grade cervical intraepithelial neoplasia (CIN2/3) in ASC-US cytology in this study were high. Colposcopy should be recommended for diagnosis and follow-up in this setting. PMID: 31870122 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
Semin Reprod Med 2019; 37: 125-130 DOI: 10.1055/s-0039-3400241Vasomotor symptoms, including hot flushes and night sweats, pose a significant symptomatic burden to women undergoing menopause, and negatively impact on both their physical and psychological well-being. Management of these symptoms can be challenging, with the use of conventional hormone replacement therapy limited by duration of treatment and clinical contraindications. Recent advances in our understanding of the neuroendocrine regulation of the reproductive axis and thermoregulation postmenopause has helped identify a promising new therapeutic target to ameli...
Source: Seminars in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Review Article Source Type: research
Excess body weight is an established risk factor for breast cancer. Research suggests that’s because too much body fat can elevate levels of sex hormones like estrogen, especially among postmenopausal women. But despite knowing there is a correlation between extra weight and breast cancer, it’s been difficult to study how losing that weight could affect an individual woman’s chance of developing cancer. Now, a new paper published in the Journal of the National Cancer Institute provides encouraging evidence that, for women 50 and older, virtually any amount of sustained weight loss translates to a reductio...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Cancer embargoed study Source Type: news
Title: New Study Shakes Up Thinking on Hormone Replacement TherapyCategory: Health NewsCreated: 12/13/2019 12:00:00 AMLast Editorial Review: 12/13/2019 12:00:00 AM
Source: MedicineNet Menopause General - Category: Primary Care Source Type: news
This study was conducted in 263,788 women aged 40–69 years at enrolment into the UK Biobank population-based cohort. Information on demographic, reproductive and health factors was collected at baseline using computerized questionnaires, while incident DCIS was ascertained through linkage to UK cancer registries. Age-adjusted and multivariable hazard ratios were estimated using Cox proportional hazards models in the total sample and by menopausal status. During an average of 7 years of follow-up, 1,016 women developed DCIS. Multivariable analysis indicated that age, physical activity, height, family history of breast...
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
Menopausal women often have vasomotor and psychological symptoms that impair significantly their quality of life [1,2]. It is well known that the hormonal and biological changes associated with menopause cause hot flushes, night sweats and urogenital symptoms [3]. On the other hand, consensus is lacking on the extent to which other symptoms, like mood changes, sleep problems, sexual complaints and problems with concentration and memory, are linked to the menopause. Interindividual differences in reporting menopausal symptoms may also depend on personality traits, i.e., how menopausal symptoms are perceived, interpreted and coped with [4].
Source: Maturitas - Category: Primary Care Authors: Source Type: research
Conclusion: This meta-analysis suggests that menopausal HRT may increase the risk of ovarian cancer, especially for serous and endometrioid tumors.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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