Cytochrome P450 1A2 Is Incapable of Oxidizing Bilirubin Under Physiological Conditions

Conclusion: Our results indicated that the region-specific expression of CYP1A2 increased during development, but CYP family enzymes were physiologically incapable of metabolizing BR. The ability of CYPs to oxidize BR may be triggered by CYP inducers.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research