Quality of life study in asymptomatic patients with hepatitis C.

CONCLUSION: these data support the hypothesis that the hepatitis C virus may worsen quality of life in asymptomatic patients. PMID: 31617364 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research

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Authors: Yamamoto S, Onishi H, Oyama A, Takaki A, Okada H Abstract A 78-year-old man with chronic hepatitis C underwent hepatectomy for hepatocellular carcinoma (HCC) 11 years prior to presentation. He was diagnosed with multiple intrahepatic recurrences of HCC with portal vein invasion and received hepatic arterial infusion chemotherapy (HAIC) with cisplatin. He developed abdominal pain, diarrhea, and blood-stained stool following treatment. Computed tomography revealed significant bowel wall thickening throughout the colon. Colonoscopy revealed reddish edematous mucosa with a reduced vascular pattern without isch...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
DiscussionThe number of studies examining ECHO and ECHO-like models of medical tele-education has been modest compared with the scope and scale of implementation throughout the USA and internationally. Given the potential of ECHO to broaden access to healthcare in rural, remote, and underserved communities, more studies are needed to evaluate effectiveness. This need for evidence follows similar patterns to other service delivery models in the literature.
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
CONCLUSION: Depression got minimally worse in the male group despite an improvement in CHC. Anxiety scores were improved with treatment in the cirrhotic and non-cirrhotic groups significantly. A decrease in anticipatory anxiety may be related to the high treatment success with DAAA. Nearly all the subitems of the QoL scores were improved after treatment and these were more common in the female group. Elimination of HCV may itself decrease the number of patients who need psychiatric treatment. PMID: 31530524 [PubMed - in process]
Source: The Turkish Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: Turk J Gastroenterol Source Type: research
ConclusionsSeptic arthritis of the lumbar facet joints is a rare condition with no more than 50 cases reported in the literature. This infection, which can cause significant morbidity, can result from local or systemic inoculation. MRI is the diagnostic method of choice. While antibiotic therapy is the first line of treatment, when it fails, surgical debridement may be necessary.
Source: European Journal of Orthopaedic Surgery and Traumatology - Category: Orthopaedics Source Type: research
This study aimed to determine whether dose and duration of opioid prescriptions predict subsequent heroin use in United States veterans. We analyzed data from 2002 to 2012 from the Veterans Aging Cohort Study, a prospective cohort study. We used inverse probability of censoring weighted Cox regression to examine the relationship between self-reported past year heroin use and 2 primary predictors: (1) prior receipt of a high-dose opioid prescription (≥90 mg morphine equivalent daily dose), and (2) prior receipt of a long-term opioid prescription (≥90 days). Heroin use was ascertained using most recent value of time-up...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
Question: A 65-year-old woman was referred to our clinic with a 12-hour history of epigastric pain and coffee-ground emesis. Her medical history included hepatitis C virus-related compensated cirrhosis, for which she was currently undergoing treatment with an interferon-free regimen of ledipasvir and sofosbuvir for the last 2 months.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Clinical Challenges and Images in GI Source Type: research
Discussion Transplantation is not a common problem for primary care physicians but when a child’s disease has progressed to end-stage organ failure, transplantation can be the only treatment available. While the primary care provider usually is not involved in the daily management of patients before, during and after transplantation, they can be involved in many areas. These can include providing appropriate primary and acute care, ordering and obtaining necessary medical tests, medications and equipment, assisting with medical insurance, providing medical history and records to consultants, translating medical infor...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Patients with chronic hepatitis C virus (HCV) infection often report neuropsychiatric, somatic, and gastrointestinal symptoms including fatigue, sleep disturbance, musculoskeletal pain, depression, and abdominal pain [1 –3]. Patients may attribute these symptoms to HCV, a chronic viral infection associated with several extrahepatic disorders. Recent studies show that health-related quality of life and other patient-reported outcomes (PROs) improve during all-oral direct-acting antiviral (DAA) therapy and after pa tients achieve a sustained virological response (SVR) [4–6].
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
Patients with chronic hepatitis C virus (HCV) infection often report neuropsychiatric, somatic, and gastrointestinal symptoms including fatigue, sleep disturbance, musculoskeletal pain, depression, and abdominal pain.1 –3 Patients may attribute these symptoms to HCV, a chronic viral infection associated with several extrahepatic disorders. Recent studies show that health-related quality of life and other patient-reported outcomes (PROs) improve during all-oral direct-acting antiviral (DAA) therapy and after pati ents achieve a sustained virologic response (SVR).
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Research Article Source Type: research
This study aimed to evaluate the impact of hepatitis C virus (HCV) clearance with DAAs on HRQoL after one year of follow-up. METHODS: this was a prospective observational study of chronic hepatitis C patients who started DAA treatment between May 2016 and April 2017 and completed the EQ-5D-5L questionnaire at baseline, 12 (post-12) and 48 (post-48) weeks after the end of treatment. Patients with SVR were analyzed in order to investigate factors associated with changes in HRQoL. RESULTS: a total of 199 patients were enrolled, 65% were male, 29% had cirrhosis and 32% had HIV co-infection. The proportion of patients w...
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
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