Topical Tranexamic Acid Is Effective in Cementless Total Knee Arthroplasty

Surgical techniques used to decrease the amount of blood lost during the procedure range from tourniquets to electrocautery and, more recently, the use of antifibrinolytics. Currently, tranexamic acid (TXA) is the most commonly used antifibrinolytic in arthroplasty procedures. It was previously thought that intravenous TXA was more effective than topical TXA, but had an increased risk of thrombosis and cardiac events; however, this study showed that topical TXA more effectively decreases blood loss and the need for a blood transfusion after hybrid fixation total knee arthroplasty (TKA) compared to cemented TKA.

Source: Orthopedic Clinics of North America - October 16, 2019 Category: Orthopaedics Authors: Stephen Chambers, Luke Tidwell, Anita Kerkhof, Richard Smith, William M. Mihalko Source Type: research