The Interaction Between Prepregnancy BMI and Gestational Vitamin D Deficiency on the Risk of Gestational Diabetes Mellitus Subtypes with Elevated Fasting Blood Glucose

To investigate the association of VitD with GDM, and examine the potential modifying effect of prepregnancy BMI in Chinese pregnant women.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Original article Source Type: research

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WEDNESDAY, May 22, 2019 -- Maternal vitamin D deficiency, as early as the first trimester of pregnancy, is associated with an increased risk for gestational diabetes mellitus (GDM), according to a study recently published in Diabetes, Obesity and...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
The objective of this systematic review and meta-analysis was to determine whether supplementation of vitamin D given to women with gestational diabetes can promote glycaemic control. EMBASE and PubMed were searched up to November, 2018. The selection criteria included randomised controlled trials of the effect of vitamin D supplementation (1000–4762 IU/day) on pregnant women with gestational diabetes mellitus. Study data and outcome measures (fasting blood glucose, glycated haemoglobin and serum insulin) were extracted from included studies. Random-effects models were used for meta-analyses. Heterogeneity tests,...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
As vitamin D deficiency is associated with an increased risk of gestational diabetes mellitus (GDM)a, we aimed to test vitamin D supplementation as a strategy to reduce GDM risk (evaluated after fasting plasma glucose (FPG)b, insulin resistance and weight gain) in pregnant overweight/obese women.
Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Original article Source Type: research
This study was conducted to illustrate the relation between vitamin D deficiency and glycemic parameters.Materials and methodsThe study was carried out on 80 pregnant females who were attending obstetrics and gynecology out-patient clinic in el-Shatby hospital in Alexandria university, Egypt. They were divided into 2 groups: group 1 (n = 40) pregnant females diagnosed with gestational diabetes de novo at week 24–28 and group 2 (n = 40) pregnant females of the same age group who were not suffering from any glucose intolerance (control group). Each patient was subjected to detailed history taking, complete phys...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionSevere vitamin D deficiency in second trimester of pregnancy is significantly associated with elevated risk for GDM.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
During pregnancy, vitamin D plays a central role in conception, implantation and development of the placenta [1]. Worldwide, vitamin D deficiency during pregnancy is considered as a major public health problem [2 –4]. Existing research indicates that vitamin D insufficiency or deficiency is related with a number of pregnancy complications such as preeclampsia, gestational diabetes mellitus, and intra uterine growth reduction [5]. Several studies have reported low serum vitamin D levels in pregnant women in India [6–8].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - Category: Biomedical Science Authors: Source Type: research
This study was assigned to evaluate relation between serum vitamin D level and insulin resistance in gestational diabetes mellitus(GDM). METHODS: This cross sectional study was done throughout one year between 2015-2016 in GDM patients (age,20-40 years). After history taking and physical examination ,the laboratory tests including : Fasting blood sugar(FBS), Glucose tolerance test(GTT), calcium, phosphorous,parathormone, 25(OH)vitamin D, insulin, HbA1C,TG,LDL,HDL were performed for all patients. Insulin resistance was calculated according to HOMA-IR formula. Vitamin D level was compared between patients with and witho...
Source: Current Diabetes Reviews - Category: Endocrinology Authors: Tags: Curr Diabetes Rev Source Type: research
AbstractIntroductionVitamin D (25OHD) and parathyroid hormone (PTH) are associated with dysglycemia, and we investigated them in gestational diabetes mellitus (GDM).MethodsIn this cross-sectional, observational study, we included 75 pregnant women between 24 and 28  weeks of gestation. A fasting venous sample was collected for plasma glucose (FPG), insulin, PTH and 25OHD. Glucose and insulin samples were collected hourly after 75 g glucose load for 2 h. Insulin sensitivity was estimated by the Matsuda index (MI) and beta cell function by the insulin secretion sensitivity index (ISSI-2). The subjects were stratified in...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
Publication date: June 2018Source: The Journal of Steroid Biochemistry and Molecular Biology, Volume 180Author(s): Karoline von Websky, Ahmed Abdallah Hasan, Christoph Reichetzeder, Oleg Tsuprykov, Berthold HocherAbstractObservational studies from all over the world continue to find high prevalence rates of vitamin D insufficiency and deficiency in many populations, including pregnant women. Beyond its classical function as a regulator of calcium and phosphate metabolism, vitamin D elicits numerous effects in the human body. Current evidence highlights a vital role of vitamin D in mammalian gestation. During pregnancy, ada...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
CONCLUSION: The present study showed 250HD insufficiency in pregnant women at midgestation which was not associated with GDM. PMID: 29944234 [PubMed]
Source: Clinical and Experimental Obstetrics and Gynecology - Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research
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