Potent anti-myeloma efficacy of dendritic cell therapy in combination with pomalidomide and programmed death-ligand 1 blockade in a preclinical model of multiple myeloma

In this study, we investigated the efficacy of DC vaccination in combination with pomalidomide and programmed death ligand-1 (PD-L1) blockade in a murine model of multiple myeloma (MM). MOPC-315 cell lines were injected subcutaneously to establish MM bearing mice.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 30, 2019 Category: Hematology Authors: Je-Jung Lee, Sung-Hoon Jung, Tan-Huy Chu, Manh-Cuong Vo, Hye-Seong Park, Hyeoung-Joon Kim Source Type: research