Daratumumab, Lenalidomide, and Dexamethasone (D-Rd) Delivers a Reduction and Delay in Worsening of Pain Symptoms for Patients with Newly Diagnosed Multiple Myeloma Ineligible for Transplant

An ongoing phase 3 trial of transplant-ineligible patients with newly diagnosed multiple myeloma (NDMM) demonstrated significant improvement in progression-free survival with daratumumab, lenalidomide, and dexamethasone (D-Rd) vs Rd alone (MAIA clinical trial; Facon T, et al. N Engl J Med. 2019;380:2104-15). Bone pain is a common presenting symptom in patients with multiple myeloma (MM), and pain has a significant impact on a person's everyday activity and health-related quality of life (HRQoL).
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Source Type: research