Screening for Gaucher disease in patients with plasma cell dyscrasias

Gaucher disease (GD) constitutes the most frequent lysosomal storage disease and is attributed to an inherited deficiency of glucocerebrosidase with an autosomal recessive pattern. Although controversial, published data have demonstrated an increased incidence of monoclonal gammopathies, especially multiple myeloma (MM) in these patients. Under this prism, we decided to perform a screening test for GD in a large number of patients with plasma cell dyscrasias (PCDs).

Source: Clinical Lymphoma, Myeloma and Leukemia - September 30, 2019 Category: Hematology Authors: Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Despina Fotiou, Nikolaos Kanellias, Magdalini Migkou, Evangelos Eleutherakis-Papaiakovou, Efstathios Kastritis, Meletios A. Dimopoulos, Evangelos Terpos Source Type: research