Long-term positive psychological outcomes in an Australian pancreatic cancer screening program
AbstractScreening for pancreatic cancer (PC) in high-risk groups aimed to detect early cancers is currently done only in the research setting, and data on psychological outcomes of screening in these populations is scarce. To determine the psychological impact of a national Australian pancreatic screening program, a prospective study was conducted using validated psychological measures: impact of events scale (IES), psychological consequences questionnaire (PCQ) and the cancer worry scale. Measures were administered at baseline, 1-month and at 1-year post-enrolment and correlations with abnormal endoscopic ultrasound (EUS) results were calculated. Over a 6-year period, 102 participants were recruited to the screening program. Thirty-nine patients (38.2%) had an abnormal endoscopic ultrasound, and two patients (2.0%) were diagnosed with PC and two with other malignancies. Those with a personal history of cancer or a positive BRCA2 mutation demonstrated significantly increased worry about developing other types of cancer at baseline (p
Condition: Pancreatic Ductal Adenocarcinoma Intervention: Device: EUSRA electrode needle connected to a radiofrequency generator (VIVA RF generator; STARmed, Seoul, S. Korea) Sponsor: Campus Bio-Medico University Not yet recruiting
In conclusion, the present case is an extremely rare occurrence of simultaneous multiple RDMs from PTC as the initial presentation.
AbstractExtension of tumor tissue within a vein is a recognized prognostic factor in abdominal malignancy because of its influence on tumor staging and selection of therapeutic management. With the advent of newer surgical techniques, and variable treatment strategies, imaging plays a crucial role in categorizing patients according to the tumor resectability and vascular reconstruction techniques during surgery. Understanding the clinical impact of tumor thrombus increases the awareness of the radiologist about the key findings in tumor staging and decision-making of surgical approach. Ultrasound (US), computed tomography ...
Condition: Pancreatic Cancer Intervention: Procedure: Endoscopic ultrasound guided fine needle aspirate Sponsor: Assiut University Recruiting
Conclusion: Patients with type 1 DM should be examined for thyroid diseases, and patients with suspected thyroid disease should be evaluated with a thyroid ultrasound. Type 1 DM and PTC coexistence albeit very rare; It should be known that type 1 diabetes can be seen together with thyroid cancer. PMID: 31686641 [PubMed - as supplied by publisher]
Endoscopic ultrasound-guided fine needle aspiration (EUS-guided FNA) fails to diagnose up to 25% of patients with pancreatic ductal adenocarcinoma (PDAC). Proteomics may help to overcome this clinical dilemma. We hypothesized that soluble protein signatures can differentiate PDAC from benign tissues.
Authors: Liu L, Huang X, Li X, Ma L, Zhao X, Yang X Abstract PURPOSE: To investigate the diagnostic value of ultrasound combined with computed tomography (CT) in pancreatic cancer. METHODS: 312 patients with pancreatic lesions treated in the Affiliated Hospital of Qingdao University were retrospectively analyzed, including 217 patients definitely diagnosed with pancreatic cancer and 95 patients diagnosed with pancreatitis. A hundred and one patients with ultrasonic diagnosis were enrolled into the ultrasound group, 98 patients with CT diagnosis were enrolled into CT group, and 113 patients undergoing ultrasound...
ConclusionsParticipants reported multiple benefits of genetic counselling and testing but continue to seek greater clarification about their individual PC risk. Extension of PancPRO is required to enable personalised PC risk assessment for all high-risk sub-groups. More detailed discussion of PC risk forBRCA2 pathogenic variant carriers, providing a written summary in all cases and a plan for genetics review were identified as areas for improvement.