A Model of In Vivo HSV-1 DNA Transport Using Murine Retinal Ganglion Cells.
We present an alternative method for studying these issues using the axonal transport of Herpes simplex virus in mature retinal neurons in vivo. Using genetically identical mice and carefully controlling the delivery of virus, an investigator can obtain insight into the transport of virus to and from the neuron cell body within the cellular environment of an intact, mature animal. This allows confirmation and extension of results seen in vitro.
PMID: 31617195 [PubMed - in process]
Source: Herpes - Category: Infectious Diseases Authors: LaVail JH Tags: Methods Mol Biol Source Type: research
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