Fear of stinging insects in relation to state anxiety and trait anxiety in a group of patients with hymenoptera venom allergy undergoing immunotherapy.

Fear of stinging insects in relation to state anxiety and trait anxiety in a group of patients with hymenoptera venom allergy undergoing immunotherapy. Postepy Dermatol Alergol. 2019 Aug;36(4):472-477 Authors: Woźniewicz A, Szynkiewicz E, Pałgan K, Graczyk M, Dowbór-Dzwonka A, Bartuzi Z Abstract Introduction: The level of fear of hymenoptera associated with stinging or envenomation may depend on situational factors and on trait anxiety characteristic of each patient. Aim: To assess the relationship between fear of stinging insects on the one hand and state anxiety and trait anxiety on the other in a group of patients with hymenoptera venom allergy. Material and methods: The study was conducted by the Department of Allergy, Clinical Immunology and Internal Diseases, Dr J. Biziel University Hospital No. 2 in Bydgoszcz, Poland. A total of 114 patients (71 women (63%) and 43 men (37%)) with hymenoptera venom allergy undergoing immunotherapy participated in the study. The State-Trait Anxiety Inventory (STAI) and a dedicated scale developed by the authors for this study were used. Results: State anxiety was found to significantly (p
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Related Links:

Bacillus Calmette-Guerin (BCG)-refractory high-grade non –muscle-invasive bladder cancer remains a challenging problem. Radical cystectomy is standard of care, but carries significant morbidity. Therefore, there is a need for effective treatments. Previous salvage intravesical therapies have had disappointing results with long-term follow-up; however, a wide array of novel agents is currently under investigation. These include novel combinations of existing intravesical agents, novel modes of delivery such as hyperthermia, viral mediated therapies, and immunotherapy. We review the need for novel treatment with existi...
Source: Urologic Clinics of North America - Category: Urology & Nephrology Authors: Source Type: research
Due to significant risks of cancer recurrence and progression, and limited options after intravesical Bacillus Calmette Guerin (BCG) therapy, there is a critical unmet need to identify novel treatments for those patients with BCG-unresponsive bladder cancer. There is active investigation of immunotherapies which provide both biologic and clinical rationales for indoleamine-2,3- dioxygenase inhibitors in salvage therapy for non-muscle invasive bladder cancer.
Source: Urologic Clinics of North America - Category: Urology & Nephrology Authors: Source Type: research
This article provides a comprehensive review of the available data for immunotherapy being used as a salvage treatment in non –muscle-invasive bladder cancer. The literature demonstrates that the immune system has an important role in bladder cancer progression. Initial results from studies using checkpoint inhibitors, recombinant interferon-α2b protein, and oncolytic adenoviruses have shown promising responses with acc eptable toxicities. However, the majority of the current data arises from small trials with limited follow-up. There are currently several ongoing studies in this setting, which we await complet...
Source: Urologic Clinics of North America - Category: Urology & Nephrology Authors: Source Type: research
Despite the 40-year reign of bacillus Calmette-Gu érin (BCG) as the most effective immunotherapy in urologic cancers, a lack of clinical tools to predict treatment response has hampered progress in the field. Acting as an immunostimulatory agent against a multitude of phenotypically diverse non–muscle-invasive bladder cancers, response to BCG li kely depends on both tumor characteristics as well as host factors. With a deeper understanding of the tumor biology as well as the mechanism of action underpinning immunotherapy, newer and more effective clinical tools are being constructed to improve patient selection.
Source: Urologic Clinics of North America - Category: Urology & Nephrology Authors: Source Type: research
Authors: Bilò MB, Tontini C, Martini M, Corsi A, Agolini S, Antonicelli L Abstract Summary: Hymenoptera venom allergy (HVA) is the most frequent cause of anaphylaxis in Europe, accounting for most of the severe reactions occurring in adults, and being the second cause of anaphylaxis in children. Prevention of further episodes in patients who developed a systemic reaction (SR) is based on the correct management of the allergic emergency, the referral to an allergist for a correct diagnosis, prescription of adrenaline auto-injectors (AAI) and specific venom immunotherapy (VIT), if recommended. Diagnosis is bas...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
CONCLUSIONS: The longest VIT duration in children and adolescents with HVA is related to the decreased anxiety of their parents. Parent's feeling of safety depends on the stage of treatment and place of residence. PMID: 31232065 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - Category: Environmental Health Authors: Tags: Ann Agric Environ Med Source Type: research
CONCLUSIONS: The gender, treatment duration and stage of anaphylactic reaction influenced level of anxiety. The level of feeling of safety was related to the place of living. PMID: 30922038 [PubMed - in process]
Source: Annals of Agricultural and Environmental Medicine : AAEM - Category: Environmental Health Authors: Tags: Ann Agric Environ Med Source Type: research
ConclusionsTherefore, particularly with regard to quality of life, it is important to ensure that all insect venom allergy patients are referred to an allergist, the indication for VIT is verified, treatment is initiated where appropriate, and sting challenge is performed during maintenance treatment.
Source: Allergo Journal International - Category: Allergy & Immunology Source Type: research
I hope everyone has been reading Mockingbird, which recently finished its first storyline. It’s a fun comic featuring an enjoyable character, good writing, and great art. Since much of the first story takes place in a SHIELD medical clinic — and since Bobbi keeps reminding us she has a doctorate in biology — I thought the series was ripe for some elucidating medical annotations. Since I don’t want this post to drag on forever, I’m going to break the storyline down into three separate posts. This first one will just deal with the first issue. Mockingbird #1 Chelsea Cain, writer Kate Niemczyk, a...
Source: Polite Dissent - Category: Primary Care Authors: Tags: newtag Source Type: blogs
Opinion statement Patients who have had an anaphylactic reaction to stinging insect should be educated on the potential of fatality from venom allergy. These patients should be referred to an allergist/immunologist, a specialist with training in the diagnosis and management of stinging insect allergy. The three tenets of treatment for stinging insect allergy are insect avoidance measures, proper use of epinephrine, and insect immunotherapy. Avoidance is ideal but not always practical. Intramuscular epinephrine is the only effective therapy for anaphylaxis. Insect immunotherapy is proven to reduce the probability o...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
More News: Allergy | Allergy & Immunology | Anxiety | Dermatology | Immunotherapy | Insect Bites & Stings | Poland Health | Skin | Study | Women