Early-life programming of pain sensation? Spinal pain in pre-adolescents with pain experience in early life

Conclusion: Experience of early-life pain is seemingly associated with spinal pain in pre-adolescence. The study highlights that early-life painful experiences can influence programming future pain responses.What is Known:•Spinal pain in pre-adolescents is common, causes marked discomfort and impairment in everyday life, and may be an important predictor of spinal pain later in life.•Neurobiological mechanisms have been suggested as involved in early programming of pain sensitization.What is New:•Pain exposure in early postnatal life in terms of infantile colic and recurrent otitis media is associated with spinal pain in pre-adolescence; thus, experience of such painful conditions in the early postnatal period may seemingly influence programming of future pain sensation.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research