WHO drafted in to help control severe dengue outbreak in Pakistan

Source: BMJ News - Category: General Medicine Source Type: research

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(Ecole Polytechnique F é d é rale de Lausanne) A new EPFL and MIT study into the interplay between mobility and the 2013 and 2014 dengue outbreaks in Singapore has uncovered a legal void around access to mobile phone data -- information that can prove vital in preventing the spread of infectious diseases.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
The objective of this study was to evaluate the anti-ZIKV IgG prevalence in blood donors from the Northeast region of the S ão Paulo State, Brazil, which experienced a ZIKV outbreak in 2016.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: RESEARCH ARTICLE Source Type: research
Authors: Maniero VC, Rangel PSC, Coelho LMC, Silva CSB, Aguiar RS, Lamas CC, Cardozo SV Abstract A progressive increase in the circulation of arboviruses in tropical countries has been observed, accounting for 700,000 yearly deaths in the world. The main objective of this article was to identify the presence of Zika (ZIKV), dengue (DENV), and Chikungunya (CHIKV) viruses in immature stages of Aedes aegypti and Ae. albopictus. Household collections of immature phases of the vectors were carried out in the years 2015 and 2016. A total of 2902 dwellings were visited and the rate of infestation with larvae and pupae of ...
Source: Brazilian Journal of Medical and Biological Research - Category: Research Tags: Braz J Med Biol Res Source Type: research
Conclusions: Aedes albopictus is responsible for the current outbreaks. The spread of Aedes albopictus and Aedes japonicus increases the risk of the autochthonous transmission of these viruses. Although native species could contribute to their transmission, more studies are still needed to assess that risk.
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
[Radio Dabanga] Khartoum -Sudan has been facing various disease outbreaks in the past months, including cholera, dengue fever, Rift Valley fever (RVF), chikungunya, and malaria. The government and humanitarian partners actively responded to the outbreaks, the UN Office for the Coordination of Humanitarian Affairs (OCHA) reports. Most complaints reaching Radio Dabanga come from the western and eastern parts of the country.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
by Tarunendu Mapder, Sam Clifford, John Aaskov, Kevin Burrage The titre of virus in a dengue patient and the duration of this viraemia has a profound effect on whether or not a mosquito will become infected when it feeds on the patient and this, in turn, is a key driver of the magnitude of a dengue outbreak. The assessment of the heterogeneity of viral dynam ics in dengue-infected patients and its precise treatment are still uncertain. Infection onset, patient physiology and immune response are thought to play major roles in the development of the viral load. Research has explored the interference and spontaneous generati...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
In conclusion, the author of this paper mentioned that immunization gap needs to be handle systematically. Immunization data released on 2017 showed that complete immunization was given only to 20% of targeted group, while almost 75% were either unvaccinated or unknown. During the outbreak of diphteria in Indonesia, the WHO also reported several countries with similar problem such as Bangladesh, Haiti and Yamen. It was shown that a coordination between doctors in clinic/hospital with public health officer to conduct an epidemiological investigation, in conjunction with giving prophylaxis and assuring the logistics of anti-...
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
We reported serological and molecular detection of SLEV in a healthy population of equids and humans from rural areas in Southeast Brazil. A plaque reduction neutralization test was applied, and neutralizing antibodies were detected in 11 individuals (4.6%) and 60 horses (21.5%). A qPCR targeting the 5′UTR region and reverse transcription-PCR (RT-PCR) targeting the non-structural protein (NS5) gene were performed and three individuals tested positive in both assays. Subsequent phylogenetic analysis confirmed SLEV circulation and its findings suggest the occurrence of an asymptomatic or subclinical presence in hum...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
A. Cousien et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
While efforts to control malaria with available tools have stagnated, and arbovirus outbreaks persist around the globe, the advent of clustered regularly interspaced short palindromic repeat (CRISPR)-based gene editing has provided exciting new opportunities for genetics-based strategies to control these diseases. In one such strategy, called “population replacement”, mosquitoes, and other disease vectors are engineered with effector genes that render them unable to transmit pathogens. These effector genes can be linked to “gene drive” systems that can bias inheritance in their favor, providing nove...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
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