Clinicopathologic Features and Genetic Characteristics of the BRCA1/2 Mutation in Turkish Breast Cancer Patients

Breast cancer has become one of the most widespread female malignancies worldwide, accounting for 25% of cancer diagnoses among women (1). It is also the first leading cause of female cancer mortality, accounting for 14.7% of cancer deaths (1). Although male breast cancer is scarce, accounting for nearly 1% of all breast cancers, the prevalence of male breast cancer is also increasing by 1.1% each year (2). The etiology of breast cancer is still unknown, and there are many factors that may increase a woman's chances of breast cancer.

Source: Cancer Genetics and Cytogenetics - October 15, 2019 Category: Genetics & Stem Cells Authors: Gulsah Cecener, Leila Sabour Takanlou, Maryam Sabour Takanlou, Unal Egeli, Gamze Guney Eskiler, Secil Aksoy, Ufuk Unal, Havva Tezcan, Isil Ezgi Eryilmaz, Mustafa Sehsuvar Gokgoz, Berrin Tunca, Erdem Cubukcu, Turkkan Evrensel, Sibel Cetintas, Ismet Tasdele Source Type: research