Trends in open abdomen management in Italy: a subgroup analysis from the IROA project

AbstractUse of open abdomen (OA) progressively acquired increasing importance with the diffusion of the damage control management of critical patients. The purpose of the present study is to identify the state of the art about the use of OA in Italy, focusing on techniques, critical issues and clinical outcomes. A prospective analysis of adult patients enrolled in the IROA, limited to the Italian participating centres was performed. 375 patients were enrolled. Mean age was 64  ± 16 years old, 56% of the patients were male, mean BMI was 26.9 ± 5.2. Main indications for using OA were secondary peritonitis (32.5%), post-operative peritonitis (22.9%) and trauma (11.7%). Main OA techniques used were commercial negative pressure wound therapy (49.6%) and Bogotà bag (27.7%). Definitive closure of the abdomen was reached in 82.4% of patients after 6 ± 7 days of OA. The primary fascia closure rate was 84.7%. Overall mortality was 29.1%. The complication rate was 50.8%, with an enteroatmospheric fistula incidence: 7.5%. A univariate analysis performed on co mplication type found the duration of OA treatment (p = 0.024) to be statistically significant. Univariate analysis on mortality risk identified as significant age, duration of OA (in days) and pancreatitis as indication; multivariate analysis confirmed age (p 
Source: Updates in Surgery - Category: Surgery Source Type: research

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ConclusionPatients and physicians' priorities in the management of epilepsy overlap only in part. Patients are satisfied with their caring physicians and less satisfied with communication and management of routine and emergency problems.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
ConclusionDespite even a low dose administration of albumin during SBP, renal dysfunction and HRS occurred less than described in literature. These results associated with cost considerations could suggest to use such an intervention during SBP or to select high risk patients who must receive albumin perfusion during SBP.
Source: Arab Journal of Gastroenterology - Category: Gastroenterology Source Type: research
Conclusions: Our consensus expert guidelines provide a uniform approach to the diagnosis and treatment of pediatric FPSD. Further research is necessary to determine the full contribution of FPSD to pediatric pancreatitis.
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Article: Pancreatology Source Type: research
Authors: Origoni M, Cristoforoni P, Mariani L, Costa S, Preti M, Sandri MT, Preti EP, Ghelardi A, Perino A Abstract HPV vaccination has been introduced in clinical practice in recent years and represents the most effective strategy of primary prevention of cervical carcinoma and of female genital preneoplastic conditions. One of the major issues of the subject is represented by vaccination coverage of the target population. Since its introduction, HPV vaccine efficacy has been progressively demonstrated also towards extragenital HPV-correlated conditions and in males too. Moreover, even subjects of older age groups...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
LivaNova is scrapping its Caisson transcatheter mitral valve replacement (TMVR) program because of declines its heart valve business has seen over the last five years. Plans now call for the London-based company to enter into a restructuring plan for its heart valve business, which brought in $130 million in revenue in 2018. Under the restructuring plan, it is expected that about 150 employees could be potentially impacted in the three sites of Saluggia, Vancouver, and Minneapolis. LivaNova’s Saluggia, Italy facility will now become dedicated to R&D and production of mechanical heart valves, rings, access...
Source: MDDI - Category: Medical Devices Authors: Tags: Cardiovascular Source Type: news
Publication date: Available online 20 November 2019Source: Food Research InternationalAuthor(s): Antonietta Cerulli, Assunta Napolitano, Milena Masullo, Jan Hošek, Cosimo Pizza, Sonia PiacenteAbstractIn Italy a particularly valuable chestnut is “Marrone di Roccadaspide”, a protected geographical indication (PGI) product, deriving from a Castanea sativa cultivar, typical of Salerno province in Campania region. As chestnut industrial processes yield a large amount of shell by-products, in this study the possibility to retrain this waste food as potential source of bioactives was investigated. The ability o...
Source: Food Research International - Category: Food Science Source Type: research
In this study, two assays consisting of 46 AIM-Indels and 31 AIM-SNPs were typed in a Tigray population sample from Northern Ethiopia. STRUCTURE analysis showed that the Tigray population is characterized by a strong (˜50%) non-African genetic component shared with European and Middle Eastern populations. The intermediate position of the Tigray sample between sub-Saharan African and European / Middle Eastern reference population samples was confirmed by principal component analysis. Both AIM panels provided effective differentiation between Tigray and sub-Saharan African populations. Classification accuracy of other ...
Source: Forensic Science International: Genetics - Category: Forensic Medicine Source Type: research
Conclusions: The predictive value of FiCE for pancreatic cancer prevalence was 47%. Histological confirmation with pancreatic juice cytology is necessary before surgical resection. PMID: 31744269 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
AbstractIn socio-economical clustering often the empirical information is represented by time-varying data generated by indicators observed over time on a set of subnational (regional) units. Usually among these units may existcontiguity relations, spatial but not only. In this paper we propose a fuzzy clustering model of multivariate time-varying data, the longitudinal fuzzy C-Medoids clustering withcontiguity constraints. The temporal aspect is dealt with by using appropriate measures of dissimilarity between time trajectories. Thecontiguity among units is dealt with adding acontiguity matrix as a penalization term in ...
Source: Social Indicators Research - Category: International Medicine & Public Health Source Type: research
AbstractPopulation aging, which is common in developed countries, highlights issues related to the health and social assistance of frail individuals. The Italian Chronic Disease Program launched by the Ministry of Health proposes the implementation of tools that stratify the population based on health and care needs and enhances the integration of existing administrative health data flows. This work has its roots in the need to identify frail individuals conveyed by an Italian Local Health Unit (LHU) of the Veneto region and organize an efficient service of care and prevention. We propose an indicator of frailty, computed ...
Source: Social Indicators Research - Category: International Medicine & Public Health Source Type: research
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