Outcome of peroral endoscopic myotomy in children with achalasia

ConclusionPOEM is a safe, effective, and durable treatment for achalasia in children. However, GER is a potential concern and should be evaluated in prospective studies before adopting POEM for the management of achalasia in children.
Source: Surgical Endoscopy - Category: Surgery Source Type: research

Related Links:

Authors: Wang YJ, Lang XQ, Wu D, He YQ, Lan CH, Xiao X, Wang B, Zou DW, Wu JM, Zhao YB, Dettmar PW, Chen DF, Yang M Abstract Background/Aims: To determine the value of salivary pepsin in discriminating sub-types of gastroesophageal refluxdisease (GERD) and GERD-related disorders. Methods: Overall, 322 patients with different sub-types of GERD and 45 healthy controls (HC) werestudied. All patients took Gastroesophageal Reflux Disease Questionnaire (GerdQ) andunderwent endoscopy and 24-hour esophageal pH monitoring and manometry. Salivary pepsinconcentration (SPC) was detected by using colloidal gold double-antib...
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
Conclusions: In Asian patients with GERD, treatment with dexlansoprazole modified-release indicates a favorable efficacy and safety profile in relieving heartburn and acid regurgitation symptoms. PMID: 31597230 [PubMed - as supplied by publisher]
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
Conclusions: Contrary to our hypothesis, we found an inverse association between serum PTH and Barrett’s esophagus. Validation of the finding and the mechanism of that association deserves further study.
Source: Journal of Clinical Gastroenterology - Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research
Authors: Sun YM, Gao Y, Gao F Abstract Background/Aims: Recently, esophageal mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave (PSPW) index have been proposed, which can increase the diagnostic role of multichannel intraluminal impedance and pH recording (MII/pH) for differentiating patients with heartburn. Therefore, our aim is to investigate the role of esophageal proximal MNBI, distal MNBI, and PSPW index in differentiating Chinese patients with heartburn. Methods: Patients with heartburn from the Beijing Anzhen Hospital, who underwent upper gastrointestinal endoscopy ...
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
ConclusionEE is more prevalent after SG compared with RYGB in a pre-bariatric surgery cohort with GERD. SG is associated with significant esophageal physiologic changes conducive to GERD and its clinical consequences.
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionsPatients submitted to LSG showed a significant and progressive increase in the presence of “de novo” GERD. Also, an increased duodenogastric reflux was seen through an open and immobile pylorus. Therefore, based on these results, it seems like LSG is a “pro-reflux” surgical procedure, which should be continuously evaluated late after surgery.
Source: Obesity Surgery - Category: Surgery Source Type: research
AbstractGastroesophageal reflux disease (GERD) is an especially common disorder in the elderly population. Its presentation in this population is often different  from that in younger patients. A greater proportion of patients experience atypical GERD symptoms rather than heartburn or regurgitation, increasing the likelihood the diagnosis will be missed or overlooked. Elderly patients more commonly present with severe erosive esophagitis and GERD complicati ons compared with younger patients, and thus may require more aggressive therapy. While diagnostic work-up and management of GERD in elderly patients is similar to...
Source: Drugs and Aging - Category: Geriatrics Source Type: research
Abstract Obesity is a global health epidemic with considerable economic burden. Surgical solutions have become increasingly popular following technical advances leading to sustained efficacy and reduced risk. Sleeve gastrectomy accounts for almost half of all bariatric surgeries worldwide but concerns regarding its relationship with gastroesophageal reflux disease (GERD) has been a topic of debate. GERD, including erosive esophagitis, is highly prevalent in the obese population. The role of pre-operative endoscopy in bariatric surgery has been controversial. Two schools of thought exist on the matter, one that bel...
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Authors: Ribolsi M, Giordano A, Guarino MPL, Tullio A, Cicala M Abstract Introduction: Gastro-esophageal reflux disease (GERD) is a very common and often debilitating disease. In the broad spectrum of GERD phenotypes, three main groups may be traditionally distinguished: 1) patients only affected by esophageal and/or extra-esophageal symptoms; 2) patients with erosive esophagitis and 3) patients with further complications. Areas covered: This review provides an overview on the current classifications of GERD patients, and their impact on their management. Expert opinion: In 2017, the GERD Consensus Working Group fo...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
Conclusions: The expression of MMP-9 is most common in severe forms compared to the mild forms of GRD. PMID: 31264989 [PubMed - in process]
Source: Cirugia y Cirujanos - Category: Surgery Authors: Tags: Cir Cir Source Type: research
More News: Acid Reflux | Boys | Children | Endoscopy | Erosive Esophagitis | Esophagogastroduodenoscopy | Gastroenterology | Gastroesophageal Reflux Disease | GERD | Panendoscopy | Study | Surgery