Radial MP2RAGE sequence for rapid 3D T 1 mapping of mouse abdomen: application to hepatic metastases

ConclusionsThe radial MP2RAGE sequence could be used for fast 3D T1 mapping, to detect and characterize metastases in regions subjected to respiratory motion.Key Points• The Cartesian encoding of the MP2RAGE sequence was modified to a radial encoding. The modified sequence enabled accurate T1measurements on phantoms and on abdominal organs of mice.• Hepatic metastases were easily detected due to high contrast. Heterogeneity in T1was measured within the metastases and between each metastasis within the same animal.• As implementation of this sequence does not require specific hardware, we expect that it could be readily available for clinical practice in humans.
Source: European Radiology - Category: Radiology Source Type: research