Epilepsy, cerebral calcifications, and gluten-related disorders: are anti-transglutaminase 6 antibodies the missing link?

Gluten-related disorders (GRDs) are a group of immune-mediated diseases with several clinical manifestations triggered by gluten ingestion (1). The three main forms of GRDs are celiac disease (CD), wheat allergy (WA) and non-celiac gluten-sensitivity (NCGS) [1,2]. GRDs often present extraintestinal symptoms. Neurological manifestations have been reported in 10 to 22% of patients with coeliac disease (CD) and include gluten ataxia, polyneuropathy, myopathy, epilepsy, leukoencephalopathy, and headache [3].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research

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Publication date: Available online 15 November 2019Source: SeizureAuthor(s): Josef Finsterer, Fulvio A. Scorza, Ana C Fiorini, Carla A. Scorza
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 15 November 2019Source: SeizureAuthor(s): Hyo Jae Kim, Ji-Ye Jeon, Hyun-Woo Kim, Sang-Ahm LeeAbstractPurposeWe compared the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) with the Patient Health Questionnaire-9 (PHQ-9) according to different antiepileptic drug (AED) loads in people with epilepsy (PWE).MethodsDepression and suicidality were assessed with the Mini International Neuropsychiatric Interview (MINI), the NDDI-E, and the PHQ-9. A receiver operating characteristic (ROC) curve analysis was used. Sensitivity and specificity of the NDDI-E and PHQ-9 were compared between an AED load
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 15 November 2019Source: SeizureAuthor(s): Niccolò Carli, Alessandro Orsini, Pasquale Striano
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 16 November 2019Source: Journal of EthnopharmacologyAuthor(s): Mallappa H. Shalavadi, V.M. Chandrashekhar, I.S. MuchchandiAbstractEthnopharmacological relevanceConvolvulus pluricaulis Choisy commonly known as Shankhapushpi, is traditionally prescribed for nerve debility, loss of memory, epilepsy and as nervine tonic. Plant also proved to have diverse pharmacological activity but the neuroprotection in ischemic stroke were not found.Aim of the studyTo investigate the effect of Convolvulus pluricaulis against bilateral common carotid artery (BCCA) occlusion induced cerebral ischemic reperfu...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
We describe the potential benefits of existing asthma and COPD therapies in treating ACO patients, and the value of a “treatable traits” approach to ACO management. Throughout the review, we highlight some of the pressing, unanswered questions surrounding ACO that are relevant to the clinical community. Ultimately, addressing these questions is necessary if we are to improve clinical outcomes for this complex and heterogenous patient population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
(CNN) — Every 15 minutes, someone in the United States dies of a superbug that has learned to outsmart even our most sophisticated antibiotics, according to a new report from the US Centers for Disease Control and Prevention. That’s about 35,000 deaths each year from drug-resistant infections, according to the landmark report. The report places five drug-resistant superbugs on the CDC’s “urgent threat” list — two more germs than were on the CDC’s list in 2013, the last time the agency issued a report on antibiotic resistance. Genetic research shows germs have become especially adep...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Featured Health Antibiotics Bacteria CNN Superbugs Source Type: news
This study assessed the effect of deep-banding nutrient-rich amendments on aggregation and dispersion of a clay subsoil in the presence and absence of wheat (Triticum aestivum) roots under controlled environment conditions. A specially-designed dual-column was set up to simulate a soil profile where a well-structured topsoil overlaid a sodic clay subsoil with an exchangeable sodium percentage (ESP) of 21%. The five amendments include a control (zero amendments), fertilizer nutrients (NPKS), wheat straw + fertilizer nutrients (straw/NPKS), poultry litter (PL) and poultry litter + controlled-release ferti...
Source: Soil Biology and Biochemistry - Category: Biology Source Type: research
Publication date: November 2019Source: Saudi Journal of Biological Sciences, Volume 26, Issue 7Author(s): Priyanka Verma, Ajar Nath Yadav, Kazy Sufia Khannam, Shashank Mishra, Sanjay Kumar, Anil Kumar Saxena, Archna SumanAbstractThe biodiversity of wheat associated bacteria was deciphered from the peninsular zone of India. A total of 264 isolated bacteria were analyzed through amplified ribosomal DNA restriction analysis (ARDRA, using three restriction enzymes Alu I, Msp I and Hae III, which led to the clustering of these isolates into 12–16 groups for the different sites at>75% similarity index, adding up to 70 g...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
In this study we have compared insecticidal efficacy of different plant materials from six commonly grown plants of Pakistan, viz. Allium sativum (Alliaceae), Zingiber officinale (Zingiberaceae), Cymbopogon citratus (Poaceae), Eucalyptus globulus (Myrtaceae), Nicotiana tabacum (Solanaceae), and Azadirachta indica (Meliaceae) against T. castaneum infesting stored wheat, rice, corn and gram pulse. Various plant parts were dried, powdered, and used as admixtures to the stored commodities in the experiments. The results have suggested that A. sativum (garlic) and Z. officinale (ginger) were more effective resulting into 15 tim...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
This study provides novel insights into the molecular mechanisms underlying the desiccation tolerance of wheat seedlings, and paves the way for more detailed molecular analysis of this remarkable phenomenon.
Source: Plant Physiology and Biochemistry - Category: Biochemistry Source Type: research
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