Normal-range thyroid-stimulating hormone levels and cardiovascular events and mortality in type 2 diabetes

Thyroid dysfunction is a risk factor for cardiovascular disease. Whether thyroid function within the normal range is a risk factor for cardiovascular disease remains uncertain. The aim of this study is to evaluate whether plasma thyroid-stimulating hormone (TSH) levels in the normal range are a risk factor for cardiovascular disease and mortality in participants with type 2 diabetes mellitus with high cardiovascular risk.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research

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Authors: Honda H, Hanayama Y, Obika M, Hasegawa K, Hamahara J, Kishida M, Hagiya H, Ogawa H, Kataoka H, Otsuka F Abstract A relationship between diabetes and depression is apparent. To clarify the clinical relevance of diabetic patients' gastroesophageal symptoms to their psychological status, we retrospectively analyzed the data from a Selfrating Depression Scale (SDS) and a Frequency Scale for Symptoms of Gastroesophageal reflux disease (FSSG) among 143 type 2 diabetic patients who visited a general medicine department. Among the 45 Japanese patients enrolled, the group with relatively high SDS scores (≥ 36) s...
Source: Acta Medica Okayama - Category: General Medicine Tags: Acta Med Okayama Source Type: research
AbstractAims/IntroductionType 2 diabetes mellitus (T2DM) is a specific risk factor for intracranial atherosclerosis. The purpose of this study is to investigate the relationship between T2DM, especially uncontrolled glycemia and intracranial plaque characteristics using high ‐resolution magnetic resonance imaging (HR‐MRI).Materials and MethodsA total of 263 patients (182 male; mean age = 62.6 ± 11.5 years) with intracranial atherosclerotic plaques detected on HR‐MRI from December 2017 to March 2019 were included in this study. Patients were divided into different groups: first, patients with and without T2DM; ...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Authors: Seo DH, Kim SH, Nam M PMID: 32098003 [PubMed - in process]
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Authors: Kim MJ, Jeon JH PMID: 32098001 [PubMed - in process]
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Authors: Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB Abstract BACKGROUND: Circulating apolipoprotein J (ApoJ) is closely associated with insulin resistance; however, the effect of exercise on circulating ApoJ levels and the association of ApoJ with metabolic indices remain unknown. Here, we investigated whether a combined exercise can alter the circulating ApoJ level, and whether these changes are associated with metabolic indices in patients with type 2 diabetes mellitus. METHODS: Postmenopausal women with type 2 diabetes mellitus were ran...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Authors: Sheu WHH, Chan SP, Matawaran BJ, Deerochanawong C, Mithal A, Chan J, Suastika K, Khoo CM, Nguyen HM, Linong J, Luk A, Yoon KH Abstract The prevalence of obesity in Asia is of epidemic proportions, with an estimated 1 billion overweight/obese individuals in the region. The majority of patients with type 2 diabetes mellitus (T2DM) are overweight/obese, which increases the risk of cardiorenal outcomes in these patients; hence, sustained reductions in body weight and visceral adiposity are important management goals. However, most of the glucose-lowering therapies such as insulin, sulfonylureas, glinides, and ...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Authors: Hur KY, Kim MK, Ko SH, Han M, Lee DW, Kwon HS, Committee of Clinical Practice Guidelines, Korean Diabetes Association, Committee of the Cooperative Studies, Korean Society of Nephrology Abstract The safety of metformin use for patients with type 2 diabetes mellitus (T2DM) and advanced kidney disease is controversial, and more recent guidelines have suggested that metformin be used cautiously in this group until more definitive evidence concerning its safety is available. The Korean Diabetes Association and the Korean Society of Nephrology have agreed on consensus statements concerning metformin use for pat...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
In contrast to insulin-dependent type 1 diabetes mellitus (T1DM), the indication for Simultaneous pancreas-kidney transplantation (SPK) in patients with type 2 diabetes mellitus (T2DM) is still ambiguous and w...
Source: BMC Endocrine Disorders - Category: Endocrinology Authors: Tags: Research article Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
In 2013, it was estimated that approximately 382 million adults worldwide were living with diabetes mellitus (DM). This number is expected to increase by 55% to reach 592 million by 2035 [1]. The Turkey Diabetes Epidemiology Research Project (TURDEP-I study) conducted in 1997 –1998 reported a national Type 2 DM prevalence of 7.2%. Subsequently, the TURDEP-II study conducted in 2010 reported that this prevalence has increased to 13.7% [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
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