Extracellular NK histones promote immune cell anti-tumor activity by inducing cell clusters through binding to CD138 receptor

ConclusionThis study demonstrates a novel immunoregulatory role of NK cells against MM cells mediated by histones, and an additional role of NK cells modulating T lymphocytes activity that will open up new avenues to design future immunotherapy clinical strategies.
Source: Journal for Immunotherapy of Cancer - Category: Cancer & Oncology Source Type: research