Methamphetamine-associated psychosis: links to drug use characteristics and similarity to primary psychosis.

Conclusions: Association of early initiation of methamphetamine with psychosis severity may suggest a lasting effect on brain development. Correlation of drug use and psychosis durations may suggest a cumulative effect of methamphetamine exposure. Less severe paranoia and negative symptoms in the methamphetamine-using group could implicate better social functioning of these patients. Further mechanistic studies are warranted. Key points Early initiation of methamphetamine use is associated with psychosis severity. Methamphetamine use duration associates with psychosis duration. Methamphetamine-associated and primary schizophrenic psychoses were similar in symptoms. Methamphetamine psychosis patients were less severe in paranoia and negative symptoms. PMID: 31609149 [PubMed - as supplied by publisher]
Source: International Journal of Psychiatry in Clinical Practice - Category: Psychiatry Tags: Int J Psychiatry Clin Pract Source Type: research