Liraglutide reduces systolic blood pressure in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials.

Liraglutide reduces systolic blood pressure in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials. Clin Exp Hypertens. 2019 Oct 15;:1-8 Authors: Zhao D, Liu H, Dong P Abstract The antidiabetic effect of liraglutide in patients with type 2 diabetes mellitus has been explored in several trials. We performed this meta-analysis determining the effects of liraglutide on blood pressure in these patients. Three electronic databases (Pubmed, Web of Science, and Cochrane Central) were searched for all published articles evaluating the effects of liraglutide on blood pressure in subjects with type 2 diabetes mellitus. Total 968 patients were included in 10 randomized, double-blind, placebo-controlled trials with a follow-up of 16 ± 9 weeks. Liraglutide 1.8 mg/day reduced systolic blood pressure (weighted mean differences -5.39 (95% confidence interval, -7.26, -3.51) mm Hg, p
Source: Clinical and Experimental Hypertension - Category: Cardiology Authors: Tags: Clin Exp Hypertens Source Type: research

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ConclusionsIn Japanese patients with type 2 diabetes mellitus, linagliptin produced sustained reductions in HbA1c and had a safety profile consistent with the established safety profile of linagliptin.Trial (NCT01650259).
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
This study was designed to evaluate the influences of long-term metformin prescription in these patients.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
A 59-year-old man with type 2 diabetes mellitus and hypertension presented to the emergency department with a 4-day history of coughing and an intermittent fever. He had received ultrasonography-guided percutaneous puncture via left flank with ethanol injection for renal cyst sclerosing therapy approximately 2  weeks earlier. On physical examination, he was well oriented and febrile (39.8°C) with high blood pressure (194/88 mm Hg) and tachycardia (heart rate 131 beats/min). His abdomen and back were soft without tenderness or erythematous change.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Visual Diagnosis in Emergency Medicine Source Type: research
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Source: Diabetes Therapy - Category: Endocrinology Source Type: research
ConclusionDiabetes prevalence was 6.9% and was higher in older people, people with hypertension, alcohol consumers and abdominally obese men.
Source: Journal of Public Health - Category: Health Management Source Type: research
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Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disease, which is increasing dramatically worldwide [1,2]. For T2DM patients with hypertension, lipid levels and blood pressure control is important to prevent cardiovascular disease complications [3,4]. Poorly controlled blood glucose can cause both macrovascular and microvascular complications [5]. Glycated hemoglobin (HbA1c) has been proven as a more comprehensive measure of total glycemic control than fasting plasma glucose, and it is highly associated with the presence of diabetic micro-vascular complications in prospective studies [6].
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A 65-year-old man was admitted with slurred speech of acute onset. He had a past medical history of type 2 diabetes mellitus, hypertension and bipolar disorder on metformin, amlodipine and lithium. He had difficulty pronouncing simple words and was speaking incoherently. He seemed confused and had difficulty walking. There had been no recent falls, head trauma or alcohol ingestion.
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Source: Journal of Nutritional Science and Vitaminology - Category: Nutrition Tags: J Nutr Sci Vitaminol (Tokyo) Source Type: research
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Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
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