Exploratory Study of MYD88 L265P, Rare NLRP3 Variants, and Clonal Hematopoiesis Prevalence in Patients With Schnitzler Syndrome

ConclusionA shared molecular mechanism accounting for the pathogenesis of inflammation in SchS remains elusive. Clonal hematopoiesis is not associated with other somatic mutations found in individuals with SchS or aCAPS.

Source: Arthritis and Rheumatology - October 13, 2019 Category: Rheumatology Authors: Shelly Pathak, Dorota M. Rowczenio, Roger G. Owen, Gina M. Doody, Darren J. Newton, Claire Taylor, Jan Taylor, Catherine Cargo, Philip N. Hawkins, Karoline Krause, Helen J. Lachmann, Sinisa Savic Tags: Brief Report Source Type: research