Nanoparticle-mediated drug delivery: blood-brain barrier as the main obstacle to treat infectious diseases in CNS.

CONCLUSIONS: The scarcity of the studies trying to understand the compatibility as well as the exact mechanisms by which NDDS might be serving to enter the CNS infected by parasites opens new possibilities for further exploratory projects. There is an urgent need for new investments and motivations in the area of nanotechnology applied to the control of parasitic infectious diseases worldwide.
PMID: 31612822 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - October 13, 2019 Category: Drugs & Pharmacology Authors: Cavalcanti Gondim BL, Silva Catarino JD, Dias de Sousad MA, Oliveira Silva M, Rezende Lemes M, Carvalho-Costa TM, Lima Nascimento TR, Machado JR, Rodrigues V, Freire Oliveira CJ, Cançado Castellano LR, da Silva MV Tags: Curr Pharm Des Source Type: research