A possible mechanism of the formation of endolymphatic hydrops and its associated inner ear disorders

The pathology of Meniere ’s disease (MD) is well established to be endolymphatic hydrops. However, the mechanism underlying deafness and vertigo of MD or idiopathic endolymphatic hydrops is still unknown. In order to evaluate the pathogenesis of deafness and vertigo in MD, it seems to be rational to investigate the interr elationship between hydrops and inner ear disorders using animals with experimentally-induced endolymphatic hydrops. In spite of intense efforts by many researchers, the mechanism of vertiginous attack has been unexplained, because animals with experimental hydrops usually did not show vertiginous a ttack.
Source: Auris, Nasus, Larynx - Category: ENT & OMF Authors: Source Type: research