Mortality After Radical Prostatectomy for Prostate CancerMortality After Radical Prostatectomy for Prostate Cancer
For localized prostate cancer, which treatment has better outcomes, radical prostatectomy or external beam radiotherapy? Journal of the National Cancer Institute
Conclusions For men with low-risk prostate cancer, EBRT was associated with higher sexual function scores at 3 yr than RP; however, for men with high-risk prostate cancer, no clinically significant difference was noted. Men with high-risk prostate cancer should be counseled that EBRT and RP carry similar sexual function outcomes at 3 yr. Patient summary In this report, we studied the urinary, sexual, bowel, and hormonal functions of patients 3 yr after undergoing prostate cancer surgery or radiation. We found that for patients with high-risk disease, sexual function was similar between surgery and radiation. We conclude th...
Conditions: Prostate Adenocarcinoma; Radiotherapy; Complications; Tomotherapy Intervention: Radiation: tomotherapy Sponsor: Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori Not yet recruiting
We conducted a multicentre feasibility study to assess the ability to randomise patients between image-guided radiotherapy (IGRT) and IGRT + high dose rate (HDR) brachytherapy boost and to adhere to appropriate radiation quality assurance standards.
Publication date: Available online 8 June 2018 Source:European Urology Author(s): Alireza Aminsharifi, Thomas J. Polascik
Men with localized prostate cancer treated with combined external beam therapy with low-dose rate brachytherapy prostate boost enrolled in a prospective population-based study reported worse bowel function at one year and worse urinary irritative function through three years compared to men treated with external beam radiation therapy alone. These side effect profiles should be discussed with patients considering combined external beam therapy with low-dose rate brachytherapy prostate boost.
Conditions: High-risk Prostate Cancer; Prostate Cancer Interventions: Drug: HSV-Tk; Drug: Valacyclovir; Drug: Bicalutamide; Drug: Leuprolide Acetate; Radiation: Brachytherapy, External beam radiotherapy; Procedure: Radical prostatectomy Sponsor: The Methodist Hospital System Not yet recruiting