Ozone-induced enhancement of airway hyperreactivity in rhesus macaques: Effects of antioxidant treatment

Ozone (O3) inhalation elicits airway inflammation and impairs treatment responsiveness in asthmatic patients. The underlying immune mechanisms have been difficult to study because of the lack of relevant experimental models. Rhesus macaques spontaneously have asthma and have a similar immune system to human subjects.

Source: Journal of Allergy and Clinical Immunology - October 14, 2019 Category: Allergy & Immunology Authors: Cameron H. Flayer, Erik D. Larson, Anjali Joseph, Sean Kao, Wenxiu Qu, Austin Van Haren, Christopher M. Royer, Lisa A. Miller, John P. Capitanio, Thais Sielecki, Melpo Christofidou-Solomidou, Angela Haczku Source Type: research