Changes of Brain DTI in healthy human subjects after 520 days isolation and confinement on a simulated mission to Mars

DiscussionLong-term confinement does have measurable effects on the microstructure of the brain white matter. We assume effects of sensory deprivation to account for the regional FA reductions seen in the right TPJ. The differences in the Corpus callosum were interpreted as due to preliminary conditions, e.g. personality traits or training effects. FA and radial diffusivity were the predominant DTI parameters with significant changes, suggesting underlying processes of myelin plasticity.
Source: Life Sciences in Space Research - Category: Biology Source Type: research