A triple drug combination targeting components of the nutrient-sensing network maximizes longevity [Developmental Biology]
Increasing life expectancy is causing the prevalence of age-related diseases to rise, and there is an urgent need for new strategies to improve health at older ages. Reduced activity of insulin/insulin-like growth factor signaling (IIS) and mechanistic target of rapamycin (mTOR) nutrient-sensing signaling network can extend lifespan and improve health...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Jorge Ivan Castillo–Quan, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Gronke, Yvonne Hinze, T. Keith Blackwell, Ivana Bȷedov, Linda Partridge Tags: Brief Reports Biological Sciences Source Type: research