Theory and simulations for RNA folding in mixtures of monovalent and divalent cations [Chemistry]

RNA molecules cannot fold in the absence of counterions. Experiments are typically performed in the presence of monovalent and divalent cations. How to treat the impact of a solution containing a mixture of both ion types on RNA folding has remained a challenging problem for decades. By exploiting the large...

Source: Proceedings of the National Academy of Sciences - October 14, 2019 Category: Science Authors: Hung T. Nguyen, Naoto Hori, D. Thirumalai Tags: Biological Sciences Source Type: research