Messenger RNA therapy as an option for treating metabolic disorders [Medical Sciences]

The use of messenger RNA (mRNA) therapy by systemic delivery to treat metabolic disorders has long been hampered by poor stability, immunogenicity, inefficient delivery, and hepatic toxicity. In contrast, other molecular therapies such as viral gene and enzyme replacement therapy (Fig. 1) have been effectively employed to successfully treat rare...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Commentaries Source Type: research