MRI links head trauma microbleeds to clinical outcome

MRI scans of patients with traumatic head injuries have revealed microbleeds...Read more on AuntMinnie.comRelated Reading: Deep-learning model detects cerebral microbleeds on MRI Key MRI markers link vascular brain injury to health risks MRI offers possible link between microbleeds, Alzheimer's Brain MRI offers new insight into blood deposits SIIM: AI can accurately detect cerebral microbleeds
Source: Headlines - Category: Radiology Source Type: news

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ConclusionMultimodal analysis conducted with various image data from PiB-PET/MRI scans showed differences in regional CBF, cortical volume, and neuronal networks in different regions, indicating that pathophysiologic and functional changes in the AD brain can be observed from various aspects of neurophysiologic parameters. Application of multimodal brain images using PET/MRI would be ideal for investigating pathophysiologic changes in patients with dementia and other neurodegenerative diseases.
Source: EJNMMI Research - Category: Radiology Source Type: research
Conclusions: In this study, we observed in middle- and old-aged individuals with neither dementia nor alcohol-related disorders that moderate lifetime alcohol intake was associated with lower cerebral AB deposition compared to a lifetime history of not drinking. Moderate lifetime alcohol intake may have a beneficial influence on AD by reducing pathological amyloid deposition rather than amyloid-independent neurodegeneration or cerebrovascular injury. The Study in Context: Report: 35% of worldwide dementia cases could be prevented by modifying these 9 modifiable risk factors Study: Drinking up to 5–8 glasses of wine...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Alzheimer-disease Alzheimers beer beta amyloid deposits brain protein dementia hard liquor mental acuity moderate drinking MRI neurodegeneration PET wine Source Type: blogs
Artificial intelligence does wonders in healthcare. The technology helped issue the first COVID-19 warning before the WHO and CDC did so. It can slash the phenomenon of alarm fatigue. IBM’s Watson Health leverages the power of A.I. to bring drugs to the market faster. And it does so while cutting costs by over 50%. Speaking of IBM Watson, while the algorithm got its name from the company’s founder Thomas J. Watson, there’s another pop culture figure attached to that name. It’s elementary; we’re talking about none other than Sherlock Holmes’ sidekick, Dr. Watson. It seems like real-wor...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence AI digital health Healthcare Medicine technology Source Type: blogs
WEDNESDAY, March 25, 2020 -- New research out of France suggests that untreated sleep apnea could raise your odds for developing Alzheimer's disease. Evidence linking the two is based on a series of neurological assessments, brain scans and sleep...
Source: - Daily MedNews - Category: General Medicine Source Type: news
Conclusions: Preliminary literature suggests that FMT may be a promising treatment option for several neurological disorders. However, available evidence is still scanty and some contrasting results were observed. A limited number of studies in humans have been performed or are ongoing, while for some disorders only animal experiments have been conducted. Large double-blinded randomized controlled trials are needed to further elucidate the effect of FMT in neurological disorders.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Molecules, Vol. 25, Pages 1425: In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [125I]Iodo-ASEM and [18F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors Molecules doi: 10.3390/molecules25061425 Authors: Cornelius K. Donat Henrik H. Hansen Hanne D. Hansen Ronnie C. Mease Andrew G. Horti Martin G. Pomper Elina T. L’Estrade Matthias M. Herth Dan Peters Gitte M. Knudsen Jens D. Mikkelsen The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Cholinergic (Ach) neurotransmission has been associated with aspects of brain attention networks. Reductions in Ach are also thought to underlie cognitive symptoms in Alzheimer's Disease (AD). In a previous study using positron emission tomography (PET) imaging to measure nicotinic Ach receptor binding in vivo, our group found that Ach receptor binding was reduced in patients with AD relative to healthy controls. Reductions were observed in areas of the brain thought to mediate attention, including the anterior cingulate cortex/medial prefrontal cortex (ACC/mPFC) and insula.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Poster Number: NR - 7 Source Type: research
AbstractPrevious studies have reported an association between tooth loss and gray matter volume (GMV) in healthy adults. The study aims to elucidate the link between tooth loss, brain volume differences, and cognitive impairment by investigating the total and regional differences in GMV associated with tooth loss in older people with and without cognitive impairment. Forty older participants with mild cognitive impairment or Alzheimer ’s disease [the cognitive impairment (CI) group] and 30 age- and sex-matched healthy participants [the control (CON) group] received T1-weighted magnetic resonance imaging scans and ass...
Source: Brain Imaging and Behavior - Category: Neurology Source Type: research
Being diagnosed with any number of neurological diseases can be scary, not only due to the progressive nature of many of these conditions, but also because they often cannot be detected until their later stages of progression. Following the failu...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Neurology Ophthalmology Source Type: blogs
DISCUSSION: Sporadic Aβ deposition is associated with white matter alterations in AD predilection areas in an age-dependent manner in cognitively normal individuals. PMID: 32147939 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
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