2000 Survival Outcomes of Neoadjuvant Chemotherapy Followed By Laparoscopic or Open Radical Hysterectomy Versus Concurrent Chemoradiation in Patients with Locally Advanced Cervical Cancer

ConclusionNeoadjuvant chemotherapy followed by laparoscopic and open radical hysterectomy seems to be a safe treatment option for locally advanced cervical cancer, in terms of similar survival outcomes and morbidity of treatment with CCRT. However, the present study is too limited to permit conclusions due to its small sample size and retrospective design despite statistical methods for adjusting confounding factors.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research

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Publication date: Available online 7 May 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Dan Zhao, Bin Li, Yating Wang, Shuanghuan Liu, Yanan Zhang, Guangwen YuanABSTRACTStudy ObjectiveTo explore the feasibility of nerve plane–sparing laparoscopic radical hysterectomy (NPS-LRH) as a simplified C1-type surgery for cervical cancer patients and to compare this technique with laparoscopic radical hysterectomy (LRH).DesignA retrospective comparative study.SettingAn academic tertiary hospital affiliated with the Chinese National Cancer Center.PatientsSix hundred fifteen patients with Fédération...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: Available online 7 May 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Dan Zhao, Bin Li, Yating Wang, Shuanghuan Liu, Yanan Zhang, Guangwen YuanAbstractStudy ObjectivesTo explore the feasibility of nerve plane-sparing laparoscopic radical hysterectomy (NPS-LRH) as a simplified C1 type surgery for cervical cancer patients, and to compare this technique with laparoscopic radical hysterectomy (LRH).DesignA retrospective comparative studySettingAn academic tertiary hospital affiliated with the Chinese national cancer center.Patients615 patients with FIGO stage Ib and IIa cervical cancer who und...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
CONCLUSIONS: RRH is safe and feasible and is associated with an improved intraoperative results and clinical oncological outcomes. The present study showed that robotic surgery, in comparison to laparoscopic approach, was associated with better perioperative outcomes because of a decrease of EBL, and similar operative time, HS and complication rate, without neglecting the long-term optimal oncologic outcomes. PMID: 29083333 [PubMed - in process]
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research
The objective of this study is to perform an economic analysis and examine the influence of procedural volume of our hospital, evaluating the accounting systems of Robotic radical hysterectomy (RRH) vs Laparoscopic radical hysterectomy (TLRH) in patients with cervical carcinoma, due to the costs widely variable and lack in literature. Costs were collected prospectively, from March 2010 to March 2016. Direct costs were determined by examining the overall medical pathway for each type of intervention. 52 patients with cervical carcinoma, which were matched by age, body mass index, tumor size, International Federation of Gyne...
Source: Updates in Surgery - Category: Surgery Source Type: research
Authors: Tanaka T, Terai Y, Ashihara K, Tsunetoh S, Akagi H, Yamada T, Ohmichi M Abstract OBJECTIVE: Our objective was to determine the feasibility and detection rates and clarify the most effective combination of injected tracer types for sentinel lymph node (SLN) mapping in uterine cervical cancer in patients who have undergone laparoscopic surgery or neoadjuvant chemotherapy (NAC). METHODS: A total of 119 patients with cervical cancer underwent SLN biopsy at radical hysterectomy using three types of tracers. The various factors related to side-specific detection rate, sensitivity, and false negative (FN) rat...
Source: Journal of Gynecologic Oncology - Category: OBGYN Tags: J Gynecol Oncol Source Type: research
AbstractPurpose of ReviewIt is well established that in carefully selected patients with early cervical cancer, fertility-sparing procedures are equally safe in terms of recurrence and mortality to the standard treatment with radical hysterectomy. This review highlights the evolution in fertility-sparing management options, with long-term evidence on oncologic and obstetrical outcomes presented.Recent FindingsThe long-term safety of radical vaginal and abdominal trachelectomy is well established. Recently published series also suggest that when patient selection is limited to tumors
Source: Current Obstetrics and Gynecology Reports - Category: OBGYN Source Type: research
The study aimed to evaluate the clinical outcomes of laparoscopic nerve-sparing radical hysterectomy (LNRH) for bulky-stage cervical cancer (lesion  ≥ 6 cm) after neoadjuvant chemotherapy (NAC).
Source: International Journal of Surgery - Category: Surgery Authors: Tags: Original Research Source Type: research
The study aimed to evaluate the clinical outcomes of laparoscopic nerve-sparing radical hysterectomy (LNRH) for bulky-stage cervical cancer (lesion  ≥ 6 cm) after neoadjuvant chemotherapy (NAC).
Source: International Journal of Surgery - Category: Surgery Authors: Tags: Original Research Source Type: research
Conclusions: The robotic approach could be considered a feasible and safe alternative to other surgical options. Multicenter randomized clinical trials with longer follow-ups are necessary to evaluate the overall oncologic outcomes of this procedure.
Source: International Journal of Gynecological Cancer - Category: Cancer & Oncology Tags: Cervical Cancer Source Type: research
To evaluate the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy (LNRH) for locally advanced cervical cancer (LACC) after neoadjuvant chemotherapy (NACT).
Source: International Journal of Surgery - Category: Surgery Authors: Tags: Original Research Source Type: research
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