Babaodan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation

ConclusionBBD could prevent and cure hepatic encephalopathy derived from both chronic and acute liver diseases. Here, we found that except for the direct improvement of blood and brain ammonia level, inflammation is likely an important target of BBD to treat hepatic encephalopathy. The anti-inflammatory role of BBD may lie in its regulation of the TLR4/MyD88/NF-κ B pathways.Graphical abstractBBD can prevent and cure hepatic encephalopathy derived from both chronic and acute liver diseases. BBD can reduce hyperammonemia as well as the systematic and neurological inflammation. Inflammation is likely an important target of BBD to treat hepatic encephalopathy and the anti-inflammatory role of BBD may lie in its regulation of the TLR4/MyD88/NF-κ B pathways.
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research