Management of Pelvic Organ Prolapse After Radical Cystectomy

This article explores the anatomy, management options, and outcomes of pelvic organ prolapse with a female cystectomy patient.Recent FindingsThere is a lack of data on surgical management outcomes for prolapse following radical cystectomy. However, most case series from tertiary referral centers show reasonable results irrespective of route of repair. As expected, the surgical planes and the reorientation of the bowel loop for urinary diversion makes any pelvic reconstruction a potential hazard and requires a high level of expertise and counseling to the patient in regard to the management of expectations.SummaryPelvic organ prolapse following radical cystectomy is uncommon but presents a significant challenge to the reconstructive surgeon.
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research

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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
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Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
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Source: Inflammation - Category: Allergy & Immunology Source Type: research
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Retinal Detachment Interventions:   Drug: Dextenza;   Drug: Prednisolone Acetate Sponsors:   Midwest Eye Institute;   Ocular Therapeutix, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Borroni RG, Diegoli M, Grasso M, Concardi M, Agozzino M, Vignini M, Arbustini E Abstract Xeroderma pigmentosum (XP) is a rare autosomal recessive disease characterized by severe cutaneous and ocular sensitivity to sunlight, leading to skin cancer. Most XP patients belong to the XP complementation groups (XP-A to XP-G), due to mutations in genes involved in nucleotide excision repair (NER). On the other hand, the XP Variant type (XP-V, OMIM#278750), which accounts for about 20% of all XP patients, is associated with normal NER function. The disease gene is POLH, which encodes polymerase η (pol η) al...
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