Non-mycosis Fungoides Cutaneous T-cell LymphomasNon-mycosis Fungoides Cutaneous T-cell Lymphomas

Primary cutaneous CD30+ T-cell lymphoproliferative disorders and their differential diagnosis are highlighted in this report from the European Society for Hematopathology. American Journal of Clinical Pathology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

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Photochem. Photobiol. Sci., 2018, Accepted Manuscript DOI: 10.1039/C8PP00170G, PerspectiveFranz Trautinger Cutaneous T-cell lymphomas (CTCL) are a heterogenous group of non-Hodgkin lymphomas arising in the skin. Mycosis fungoides (MF), the most common variant, is characterised by clonal proliferation of skin residing... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Photochem. Photobiol. Sci. latest articles - Category: Chemistry Authors: Source Type: research
This article is protected by copyright. All rights reserved. PMID: 30298903 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Establishing a registry and prognostic index for mycosis fungoides, the most common type of cutaneous T-cell lymphoma (CTCL), and Szary syndrome, a rare type of CTCL, is important to improve the mana... Author: VJHemOnc Added: 10/02/2018
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
A novel CD47-blocking checkpoint inhibitor has shown promising interim results in a multicenter Phase I trail for relapsed/refractory mycosis fungoides and Szary syndrome, the most common types of cu... Author: VJHemOnc Added: 10/02/2018
Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
This article is protected by copyright. All rights reserved. PMID: 30269331 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Mogamulizumab (Poteligeo) is indicated for  relapsed or refractory mycosis fungoides or Sézary syndrome following at least one prior systemic therapy.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
AbstractCutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of lymphomas that are characterized by primary skin involvement. Mycosis fungoides (MF) and S ézary syndrome (SS), the two most common subtypes of CTCL, can be difficult to manage clinically as there are few effective treatment options available. Recently, histone deacetylase inhibitors (HDACi) have emerged as promising therapies with favorable adverse effect profiles, compared with traditi onal chemotherapies. In this article, we review the published literature to evaluate the role of HDACi in the treatment of CTCL. Specifically, we (1) briefly di...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Aim: Mycosis Fungoides (MF) is a cutaneous T-cell lymphoma variant that, in early disease, is often difficult to differentiate from inflammatory dermatoses. Mild spongiosis may be present, but significant spongiosis is exceedingly rare. In a series of 745 biopsies of early/patch MF, only 4% were found to have marked spongiosis. Accepted criteria to confirm MF include epidermotropism of atypical lymphocytes without spongiosis, or epidermotropism out of proportion to any spongiosis that may be present.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
We present two patients with indolent cutaneous T-cell lymphoma (CTCL) who had a clonal leukemic fraction of sCD3-, cCD3+, sCD4+ T-cell cells with less cell atypia. The cutaneous lesion of case 1 (60s, female) showed epidermotropic and perivascular infiltration of cCD3+, CD4+ T-cells, the features of which were consistent with those of mycosis fungoides, while in case 2 (50s, male), the diagnosis of CTCL was not confirmed histologically.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Mycosis fungoides is a primary cutaneous T cell lymphoma with unfavorable prognosis for the advanced stages of the disease. Refractory disease and advanced-staged disease require systemic therapy.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
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