2289 Supraumbilical Abdominal Fibromatosis Mimicking Exophytic Fibroids in Pregnancy
Introduction: The relation between pregnancy and uterine fibroids is not completely known yet; recent evidences report that fibroids may undergo size modification during pregnancy, with a non-linear trend of increasing volume in early pregnancy, a slowdown by mid-pregnancy and a stabilization or initial regression in the third trimester. However, the effect of the “entire” pregnancy, including childbirth and post-partum, on pre-existing uterine fibroids and in the evolution of uterine fibromatosis as a disease must be better clarified.
Chitra L Patil, Rajesh P Gaikwad, Akshaya B Banodkar, Nilofar B Attar, Gulnar D SethnaIndian Journal of Dental Research 2018 29(5):678-682The peripheral giant cell granuloma (PGCG) is a benign oral lesion occurring on the gingiva and alveolar ridge. It is the most common oral lesion and occurs at an average age of 30 years. The upsurge in the levels of estrogen and progesterone in pregnancy leads to a plethora of changes in various parts of human body, including the oral cavity. In the oral cavity, changes are commonly seen on the gingiva. These include pyogenic granuloma, PGCG and also peripheral ossifying fibroma, etc., ...
In conclusion, desmoid tumors are rare and most are sporadic. However, they may also be associated with familial adenomatous polyposis syndrome. It must be emphasized that our patient did not have any risk factors and the anatomical location in the oesophago-gastric union is not a common location. Desmoid fibromatosis supposes a clinical challenge for diagnosis and treatment and thus, management should be individualized. PMID: 30168335 [PubMed - as supplied by publisher]
The objective of this work was to report a case where cerclage was indicated owing to systemic conditions against surgical removal. The patient was a 63-year-old black man with a clinically extensive node in the buccal mucosa, pediculated, painless, measuring 50 mm, pinkish, smooth and bright surfaced, suggestive of fibrous hyperplasia or fibroma.
Rationale: Only 4.5% of brown tumors involve facial bones; of these, solitary bone involvement is usual. Brown tumors of multiple facial bones are extremely rare. Here, we report the case of a brown tumor of multiple facial bones initially misdiagnosed as an odontogenic cyst. Patient concerns: A pregnant 26-year-old woman was referred to our hospital with painful swelling of multiple facial bones, anemia, urinary calculi, marasmus, and a history of multiple bone fractures. Laboratory examination revealed an elevated serum calcium level of 3.09 mmol/L (normal range: 2.0–2.8 mmol/L) and a low phosphorus level ...
Authors: Lepage J, Merlot B, Lucot JP, Subtil D Abstract When bulky fibroids are discovered during pregnancy, they can become acutely complicated. The question of their resection thus arises. The authors report a case of a woman who was diagnosed at eight weeks' gestation by ultrasound and then by MRI, with a uterine fibroma measuring 22x12x15 cm. PMID: 29944245 [PubMed]
CONCLUSION: No significant difference was noted between single cardiac tumours and multiple tumours regarding the degree of fetal heart damage. Cardiac rhabdomyoma is the most common cardiac tumour in fetus. The correlation between cardiac rhabdomyoma and TSC is high regardless of the presence of single or multiple tumours. This article is protected by copyright. All rights reserved. PMID: 29877000 [PubMed - as supplied by publisher]
ConclusionsThe diagnosis of desmoid-type fibromatosis is usually incidental and challenging. Pathological and immunohistochemical testing are essential for confirming diagnosis where demonstration of β-catenin nuclear staining is probably the single most important characteristic. Other markers, such as vimentin, are usually positive, while S100 protein is usually negative. Our case however, confirms that there are rare cases that can be S100 positive. This is the first diagnosed case of pancrea tic desmoid-type fibromatosis with S100 protein positivity.
Discussion Neural tube defects are a group of disorders that arise during embryogenesis. They include anenephaly, exencephaly, meningmyelocoeles and encephalocoeles and other malformations including occult spinal dysraphism. Occult spinal dysraphism (OSD) has incomplete fusion of the midline elements of the spine including the bony, neural, and mesenchymal tissues but the abnormalities are covered by skin (ectodermal tissues) and therefore are not obvious. OSD has a higher risk of tethered spinal cord syndrome or other neurological/neurosurgical problems. Normally the caudal end of the spinal cord, the conus medullaris, ha...
This study suggests that women of child bearing potential employ effective methods of contraception while being treated with MEDI-570.