Optimal tumour control for early-stage non-small-cell lung cancer: A radiobiological modelling perspective

Lung cancer remains the most common cause of cancer mortality, with approximately 1.81 million patients diagnosed with the disease in 2012 [1]. The two main categories of lung cancer are non –small-cell lung cancer (NSCLC), which includes 80% of all lung cancers, and small-cell lung cancer (SCLC), which accounts for the remaining 20% [2]. Radical surgery remains a treatment mainstay for early-stage NSCLC; however, many patients with NSCLC are not candidates for surgery due to comorbid ities, such as cardiopulmonary dysfunction, stage I, II or chronic obstructive pulmonary disease or tumour size during stages III and IV [3], or because they refuse surgery altogether.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Original paper Source Type: research